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Article
Open AccessDay-care, early common infections and childhood acute leukaemia: a multicentre French case–control study
We conducted a case–control study to investigate the role of early infections in the aetiology of childhood acute leukaemias. The study included 280 incident cases (240 acute lymphoblastic leukaemia and 40 acu...
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Article
Open AccessPrognostic study of continuous variables (white blood cell count, peripheral blast cell count, haemoglobin level, platelet count and age) in childhood acute lymphoblastic leukaemia. Analysis of a population of 1545 children treated by the French Acute Lymphoblastic Leukaemia Group (FRALLE)
Many cutpoints have been proposed to categorize continuous variables in childhood acute lymphoblastic leukaemia (white blood cell count, peripheral blast cell count, haemoglobin level, platelet count and age),...
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Article
ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) WITH TEL-AML1 FUSION RNA. CLINICAL AND BIOLOGICAL FEATURES IN 17 CHILDREN TREATED WITH A UNIQUE PROTOCOL. 140
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Article
6 TESTICULAR IRRADIATION (TI) FOR ACUTE LYMPHOBLASTIC LEUKEMIA (ALL): LONG TERM FOLLOW-UP OF LEYDIG CELL FUNCTION AND PUBERTAL DEVELOPMENT
Leydig cell insufficiency is a frequent complication of bilateral TI with 24 gy (NEJM 1983). To describe the long term follow-up and the testosterone (T) deficiency we studied, with an interval time since TI >...
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Article
4 VINCRISTINE LOADED PLATELETS IN TIE TREATMENT OF IDIOPATHIC THROMBOCYTOPENIC PURPURA (ITP)
Chronic ITP is the most common autoimmune disorder in childhood. Splenectomy is prohibided before 5 years old and after is successfull in only 70 % of the cases With corticosteroids some chronic ITP seem to re...