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Article
Open AccessSWATH-MS identification of CXCL7, LBP, TGFβ1 and PDGFRβ as novel biomarkers in human systemic mastocytosis
Mastocytosis is a rare myeloproliferative disease, characterised by accumulation of neoplastic mast cells in one or several organs. It presents as cutaneous or systemic. Patients with advanced systemic mastocy...
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Article
Open AccessAdapting evidence-informed population health interventions for new contexts: a sco** review of current practice
Implementing evidence-informed population health interventions in new contexts often requires adaptations. While the need to adapt interventions to better fit new contexts is recognised, uncertainties remain r...
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Open AccessAdapting evidence-informed complex population health interventions for new contexts: a systematic review of guidance
Adapting interventions that have worked elsewhere can save resources associated with develo** new interventions for each specific context. While a develo** body of evidence shows benefits of adapted interv...
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Article
Open AccessAssociations between school-based peer networks and smoking according to socioeconomic status and tobacco control context: protocol for a mixed method systematic review
Smoking remains a major public health concern. School-based social networks influence uptake of smoking among peers. During the past two decades, the UK macro-systemic context within which schools are nested a...
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Article
Open AccessDeconstructing knowledge brokering for commissioned rapid reviews: an observational study
Knowledge brokers are increasingly used by policy agencies, yet little is known about how they engage with policy-makers and facilitate discussions with them about their research needs. This study examines kno...
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Article
Melt inclusion evidence for CO2-rich melts beneath the western branch of the East African Rift: implications for long-term storage of volatiles in the deep lithospheric mantle
We present new major element, trace element, and volatile (H2O, CO2, S, F, and Cl) concentrations of olivine-hosted melt inclusions from five high-K, low-silica basanites from the western branch of the East Afric...
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Article
Clinopyroxene–liquid thermometers and barometers specific to alkaline differentiated magmas
We present new thermometers and barometers based on clinopyroxene–liquid equilibria specific to alkaline differentiated magmas. The new models were calibrated through the regression analyses of experimental da...
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Article
Open AccessMRSA: the transmission paradigm investigated
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Article
Reflecting on stakeholders’ perceptions in an Ecological Risk Assessment workshop: Lessons for practitioners
A new form of Ecological Risk Assessment aims to improve environmental decision-making through strong stakeholder engagement, often in workshop situations. This wider focus increases interaction between worksh...
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Article
Construction and characterisation of a hexaploid wheat (Triticum aestivum L.) BAC library from the reference germplasm ‘Chinese Spring’
Hexaploid wheat (Triticum aestivum L.) is one of the most important crops in the world with 582, 691, 612 million tonnes produced in 2001 on one third of the world’s cultivated area. It has a very large genome (1...
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Article
Characterization of grapefruit plants (Citrus paradisi Macf.) transformed with citrus tristeza closterovirus genes
Grapefruit (Citrus paradisi Macf. cv Duncan) plants were transformed with several sequences from citrus tristeza closterovirus (CTV) that varied in terms of position in the CTV genome and virus strain origin in ...
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Article
An evaluation of factors affecting the efficiency of Agrobacterium-mediated transformation of Citrus paradisi (Macf.) and production of transgenic plants containing carotenoid biosynthetic genes
An improved protocol for Agrobacterium-mediated transformation of Duncan grapefruit (Citrus paradisi Macf.) epicotyl explants was developed by examining the effects of six different factors on the efficiency of ...
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Article
Central extensions of gauge groups revisited
We present an explicit construction for the central extension of the group Map(X, G) where X is a compact manifold and G is a Lie group. If X is a complex curve we obtain a simple construction of the extension b...
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Article
A simple PCR-based method for scoring the ph1b deletion in wheat
The amplified fragment length polymorphism (AFLP) technique was used to isolate DNA sequences present in the euploid wheat Chinese Spring but not in the Chinese Spring ph1b mutant (which has a deletion of the Ph1
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Article
Balanced Topological Field Theories
We describe a class of topological field theories called “balanced topological field theories”. These theories are associated to moduli problems with vanishing virtual dimension and calculate the Euler chara...
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Article
Flow cytometric analysis of the chromosomes and stability of a wheat cell-culture line
A rapidly growing, long-term suspension culture derived from Triticum aestivum L. (wheat) was synchronized using hydroxyurea and colchicine, and a chromosome suspension with 2–3 × 106 chromosomes ml−1 was made. A...
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Article
The effect of a silane coupling agent on water adsorption at a metal/polymer interface studied by neutron reflectivity and angle-resolved X-ray photoelectron spectroscopy
Neutron reflectivity and angle-resolved X-ray photoelectron spectroscopy (XPS) have been used to examine the adsorption of water to a molybdenum/polyurethane interface. The initial quasi-steady state interfaci...
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Article
Refinement of the X-linked cleft palate and ankyloglossia (CPX) localisation by genetic map** in an Icelandic kindred
The gene responsible for X-linked cleft palate and ankyloglossia (CPX) has previously been localized to the proximal region of the q arm of the X chromosome in both Icelandic and North American Indian kindreds...
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Article
Organization of retro-element and stem-loop repeat families in the genomes and nuclei of cereals
Sequences homologous to the retro-element BIS-1 and the stem-loop repeat Hi-10 are present in the genomes of a number of cereal species. A detailed characterization of these elements indicated that they are no...
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Article
Mesh selection for stiff two-point boundary value problems
This paper is concerned with the mesh selection algorithm of COLSYS, a well known collocation code for solving systems of boundary value problems. COLSYS was originally designed to solve non-stiff and mildly s...