15 Result(s)

Article

Human peripheral blood monuclear cells transfected with messenger RNA stimulate antigen-specific cytotoxic T-lymphocytes in vitro

The efficiency of test vaccines needs to be evaluated by quantification of the triggered cellular immune response. Usually, for these assays, autologous target cells expressing the vaccine antigen are required...

R. Teufel, J.-P. Carralot, B. Scheel… in Cellular and Molecular Life Sciences CMLS (2005)

Article

Rituximab mediates in vitro antileukemic activity in pediatric patients after allogeneic transplantation

Relapse is a major problem after allogeneic transplantation in children with acute B-lineage lymphoblastic leukemias (ALL) and lymphomas and additional therapeutic strategies are needed to increase graft versus l...

M Pfeiffer, S Stanojevic, T Feuchtinger, J Greil… in Bone Marrow Transplantation (2005)

Article

CD4⁺ T cell-mediated immunity against prion proteins

The prion protein (PrP^C) is essential for susceptibility to transmissible spongiform encephalopathies. A specific conformer of this protein (PrP^Sc) is, according to the 'protein only' hypothesis, the principal o...

L. Stoltze, H. Rezaei, G. Jung, J. Grosclaude… in Cellular and Molecular Life Sciences CMLS (2003)

Article

Degradation of desferrioxamines by Azospirillum irakense: Assignment of metabolites by HPLC/electrospray mass spectrometry

Based on a recent finding that an Azospirillum isolate ASP-1 possessing high 16S rDNA similarity to Azospirillum irakense was able to degrade desferrioxamine type siderophores (Winkelmann et al. BioMetals 9, 7...

G. Winkelmann, B. Busch, A. Hartmann, G. Kirchhof, R. Süßmuth, G. Jung in Biometals (1999)

Article

pCOR: a new design of plasmid vectors for nonviral gene therapy

A totally redesigned host/vector system with improved properties in terms of safety has been developed. The pCOR plasmids are narrow-host range plasmid vectors for nonviral gene therapy. These plasmids contain...

F Soubrier, B Cameron, B Manse, S Somarriba, C Dubertret, G Jaslin, G Jung… in Gene Therapy (1999)

Article

Two types of modified cardiac Na⁺ channels after cytosolic interventions at the α-subunit capable of removing Na⁺ inactivation

Failure of inactivation is the typical response of voltage-gated Na⁺ channels to the cytosolic presence of proteolytic enzymes, protein reagents such as N-bromoacetamide (NBA) or iodate, and antibodies directed ...

I. Benz, W. Beck, W. Kraas, D. Stoll, G. Jung, M. Kohlhardt in European Biophysics Journal (1997)

Article

Effects of polycations on ion channels formed by neutral and negatively charged alamethicins

The effects of the peptide polycations salmon protamine (M _r = 4332,z = + 21) and poly-l-lysine (M _r ≅ 100,00,z ≅ + 775) on ion channels formed by synthetic alamethicin Alm-F30 (one negative charge), natural Alm-...

T. Rink, H. Bartel, G. Jung, W. Bannwarth, G. Boheim in European Biophysics Journal (1994)

Article

Purification and chemical characterization of staphyloferrin B, a hydrophilic siderophore from staphylococci

This paper describes the chemical characterization of staphyloferrin B, a new complexone type siderophore isolated from low iron cultures of Staphylococcus hyicus DSM 20459. Purification of the very hydrophilic m...

H. Drechsel, S. Freund, G. Nicholson, H. Haag, O. Jung, H. Zähner, G. Jung in Biometals (1993)

Article

Microtubules and cell sha** in the mesophyll ofNigella damascena L.

Cell sha** in the mesophyll ofNigella damascena was investigated with the aim of determining the origin of the arm-like protrusions, which are characteristic of, e.g., arm-palisade cells. It was found that hoop...

W. Wernicke, P. Günther, G. Jung in Protoplasma (1993)

Article

Cell sha** and microtubules in develo** mesophyll of wheat (Triticum aestivum L.)

Differentiated mesophyll cells ofTriticum aestivum (cv. Star) exhibit a lobed outline resembling tube-shaped balloons with almost regularly spaced constrictions. It was shown that these constrictions are probably...

G. Jung, W. Wernicke in Protoplasma (1990)

Article

Molecular shape and dipole moment of alamethicin-like synthetic peptides

The peptides Boc-(l-Ala-Aib-l-Ala-Aib-l-Ala)_n-OMe, with n=2 (P10) and n=4 (P20), have been synthesized as purely hydrophobic models of the antibiotic alamethicin, which is known to be a voltage-dependent pore for...

V. Rizzo, G. Schwarz, K. -P. Voges, G. Jung in European Biophysics Journal (1985)

Article

Alamethicin pore formation: Voltage-dependent flip-flop of α-helix dipoles

The voltage-dependency of alamethicin pore formation is explained by a flip-flop gating mechanism of single alamethicin molecules. The energetically preferred aggregate structure is changed from antiparallel t...

G. Boheim, W. Hanke, G. Jung in Biophysics of structure and mechanism (1983)

Article

Biological activity of the antitumor protein neocarzinostatin coupled to monoclonal antibody by N-succinimidyl 3-(2-pyridildithio) propionate (SPDP)

G. Lüders, W. Köhnlein, G. Jung in Biophysics of structure and mechanism (1981)

Article

Nosiheptide, a sulfur-containing peptide antibiotic isolated fromStreptomyces actuosus 40037

Nosiheptide (9671 R.P.) isolated fromStreptomyces actuosus 40037 (NRRL 2954) is a sulfur-containing polypeptidic antibiotic, quite different from all the other members of this family. Very active in vitro against...

F. Benazet, M. Cartier, J. Florent, C. Godard, G. Jung, J. Lunel, D. Mancy… in Experientia (1980)