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Article
Effect of phenformin on substrate metabolism of working muscle in maturity onset diabetics
The effect of biguanides on substrate metabolism of muscle was studied by measurement of arterial and deep venous concentrations of glucose, lactate pyruvate and oxygen and of forearm blood flow in 6 maturity ...
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Article
Effect of phenformin on hepatic balances of gluconeogenic substrates in man
The effect of a five day pretreatment with phenformin (3 x 50 mg daily) on hepatic metabolism was studied in six healthy volunteers. Arterial and hepatic venous concentrations of substrates and hepatic blood f...
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Article
On gluconeogenesis of human liver
In 8 subjects in whom portal vein catheters had been inserted 5–6 days previously during cholecystectomy, arterial and portal concentrations of glucose, lactate, pyruvate, glycerol, alanine, free fatty acids,β-hy...