1,257 Result(s)

Article

Correction: A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology

**n Wang, Qian Liu, Hai-tao Yu, Jia-zhao **e… in Signal Transduction and Targeted Therapy (2024)

Article

Differences of clinical phenotype between familial and sporadic Crohn’s disease in East China

Family history is one of the strongest risk factors for inflammatory bowel diseases (IBD) while studies about the clinical phenotype of familial IBD are limited. This study aimed to compare the phenotypic feat...

Siyuan Dong, **aoxia **ang, Yu Zhang… in International Journal of Colorectal Disease (2024)

Article

Exosomes derived from human urine–derived stem cells ameliorate IL-1β-induced intervertebral disk degeneration

Human intervertebral disk degeneration (IVDD) is a sophisticated degenerative pathological process. A key cause of IVDD progression is nucleus pulposus cell (NPC) degeneration, which contributes to excessive e...

Guang Qian, Yueming Yu, Youhai Dong, Yang Hong… in BMC Musculoskeletal Disorders (2024)

Article

Association of resection margin distance with anastomotic recurrence in stage I-III colon cancer: data from the National Colorectal Cancer Cohort (NCRCC) study in China

Few studies have focused on anastomotic recurrence (AR) in colon cancer. This study aimed to clarify the association of resection margin distance with AR and compare the prognosis with nonanastomotic local rec...

Fei Huang, Shan Jiang, Ran Wei, Tixian **ao… in International Journal of Colorectal Disease (2024)

Article

“Textbook outcome(s)” in colorectal surgery: a systematic review and meta-analysis

Textbook outcome (TO) is a composite measure used in surgery to evaluate post operative outcomes. No review has synthesised the evidence in relation to TO regarding the elements surgeons are utilising to infor...

Benjamin M. Mac Curtain, Wanyang Qian… in Irish Journal of Medical Science (1971 -) (2024)

Article

Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease

Wnts are secreted, lipid-modified proteins that bind to different receptors on the cell surface to activate canonical or non-canonical Wnt signaling pathways, which control various biological processes through...

Lifang Hu, Wei Chen, Airong Qian, Yi-** Li in Bone Research (2024)

Article

Obesity, abdominal obesity, metabolic obesity phenotypes, and Helicobacter pylori infection: results from NHANES 1999–2000

Recent studies on the association between Helicobacter pylori (H. pylori) infection and obesity have reported conflicting results. Therefore, the purpose of our study was to investigate the association of obesity...

Danni Chen, Shiling Wang, Wei Yang, Hong Lu, Qian Ren in BMC Infectious Diseases (2024)

Article

Correction: Impact of non-pharmaceutical interventions during COVID-19 on future influenza trends in Mainland China

**aofan Liu, Ying Peng, Zhe Chen, Fangfang Jiang, Fang Ni… in BMC Infectious Diseases (2024)

Article

A novel technique for NO.253 lymph node dissection and left colic artery preservation to avoid potential postoperative internal hernia in laparoscopic radical resection for rectal cancer

The preservation of the left colic artery (LCA) has emerged as a preferred approach in laparoscopic radical resection for rectal cancer. However, preserving the LCA while simultaneously dissecting the NO.253 l...

Wenjun Luo, Fugen Li, Chuan Qian, Tingting Lu, Yanling **ao, Zhengwen Xu… in BMC Surgery (2024)

Article

Correction: Profiling chromatin accessibility in pediatric acute lymphoblastic leukemia identifies subtype-specific chromatin landscapes and gene regulatory networks

Jonathan D. Diedrich, Qian Dong, Daniel C. Ferguson, Brennan P. Bergeron… in Leukemia (2024)

Article

Quantitative assessment of preoperative brain development in pediatric congenital heart disease patients by synthetic MRI

This study investigated the quantitative assessment and application of Synthetic MRI (SyMRI) for preoperative brain development in children with congenital heart disease (CHD).

Shengfang Xu, Zihan Ma, **long Zhang, Shaoyu Wang, **n Ge… in Insights into Imaging (2024)

Article

Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4

The combination of programmed cell death protein 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4) antibodies has potential for enhancing clinical efficacy. We described the development and antitumor acti...

Jianyao Zeng, Yuan Fang, Zixuan Zhang, Zhenzhen Lv, **aodie Wang, Qian Huang… in Oncogene (2024)

Article

Assessment of OCT-Based Macular Curvature and Its Relationship with Macular Microvasculature in Children with Anisomyopia

To evaluate the intraocular differences in optical coherence tomography (OCT)-based macular curvature index (MCI) among children with anisomyopia and to investigate the relationship between MCI and the macular...

Yue Wu, **n Liu, Yuying Liu, Wenzhe Qian, Liandi Huang… in Ophthalmology and Therapy (2024)

Article

B cell lymphoma 6 promotes hepatocellular carcinoma progression by inhibiting tumor infiltrating CD4⁺T cell cytotoxicity through ESM1

Immunotherapy exhibited potential effects for advanced hepatocellular carcinoma, unfortunately, the clinical benefits are often countered by cancer adaptive immune suppressive response. Uncovering the mechanis...

Jiatao Li, Juan Feng, Ziyong Li, Yuanli Ni, Limei Liu, **a Lei… in npj Precision Oncology (2024)

Article

Activation of lncRNA DANCR by H3K27 acetylation regulates proliferation of colorectal cancer cells

The long noncoding DANCR functions as a tumor oncogene in many cancers, including colorectal cancer (CRC). However, the molecular mechanism of DANCR in CRC has not been explored. This study probed the function...

Yue Han, Ti-Dong Shan, Hai-Tao Huang, Ming-Quan Song, Li Chen, Qian Li in Discover Oncology (2024)

Article

The non-invasive serum biomarkers contributes to indicate liver fibrosis staging and evaluate the progress of chronic hepatitis B

This study aimed to evaluate the diagnostic abilities of the non-invasive serum biomarkers to predict liver fibrosis staging and evaluate the progress of hepatitis B.

Shaoxiong Zeng, Zhenzhen Liu, Bilun Ke, Yiwang Zhang, Qian Wang… in BMC Infectious Diseases (2024)

Article

Is there really an accelerated phase of chronic myeloid leukaemia?

Robert Peter Gale, Qian Jiang, Jane F. Apperley, Andreas Hochhaus in Leukemia (2024)

Article

0.75% ropivacaine may be a suitable drug in pregnant women undergoing urgent cesarean delivery during labor analgesia period

3% chloroprocaine (CP) has been reported as the common local anesthetic used in pregnant women undergoing urgent cesarean delivery during labor analgesia period. However, 0.75% ropivacaine is considered a prom...

**n Men, Qian Wang, Jia-fu Dong, Pei Chen, **ao-xiao Qiu, Yin-qiu Han… in BMC Anesthesiology (2024)

Article

Effect of acupuncture on tic disorder: a randomized controlled clinical trial based on energy metabolomics and infrared thermography

Acupuncture is a method for treating tic disorder. However, there is a lack of sufficient clinical objective basis in regards of its treatment efficacy. Indeed, there are structural abnormalities present in en...

Yi-ming Fan, Ying-xin Li, Yi Zhang, Dong Chen… in BMC Complementary Medicine and Therapies (2024)

Article

Mutant TP53 promotes invasion of lung cancer cells by regulating desmoglein 3

Targeted therapies have markedly improved the prognosis of lung cancer patients; nevertheless, challenges persist, including limited beneficiary populations and the emergence of drug resistance. This study inv...

Yu Feng, Rulin Qian, Dong Cui, Jiaqiang Luan… in Journal of Cancer Research and Clinical On… (2024)