166 Result(s)

Article

Erratum: Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma

Correction to: Leukemia (2012) 26, 2114–2123; doi:10.1038/leu.2012.71 Since the publication of this article, the authors have identified an error contained within Figure 1, namely that it contained the same im...

J Yang, J He, J Wang, Y Cao, J Ling, J Qian, Y Lu, H Li, Y Zheng, Y Lan, S Hong… in Leukemia (2015)

Article

Retraction Note to: Randomized clinical trial of arginine-supplemented enteral nutrition versus standard enteral nutrition in patients undergoing gastric cancer surgery

Hongyan Zhao, Hongying Zhao, Yu Wang… in Journal of Cancer Research and Clinical On… (2015)

Article

A novel Lin−CD34+CD38− integrin α2− bipotential megakaryocyte–erythrocyte progenitor population in the human bone marrow

W M Wong, M Dolinska, M Sigvardsson, M Ekblom, H Qian in Leukemia (2016)

Article

A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity

Tumor escape from immune-mediated destruction has been associated with immunosuppressive mechanisms that inhibit T-cell activation. A promising strategy for cancer immunotherapy is to disrupt key pathways regu...

Hongwei Tian, Gang Shi, Qin Wang, Yiming Li… in Signal Transduction and Targeted Therapy (2016)

Article

ASAP3 regulates microvilli structure in parietal cells and presents intervention target for gastric acidity

Gastric acidity-associated disorders such as peptic ulcer and reflux diseases are widespread, and the reported resistance and side effects of currently used medicines suggest an urgent requirement for alternat...

** Qian, Yueyuan Li, Han Yao, Haiying Tian… in Signal Transduction and Targeted Therapy (2017)

Article

Decitabine priming prior to low-dose chemotherapy improves patient outcomes in myelodysplastic syndromes-RAEB: a retrospective analysis vs. chemotherapy alone

The aim of this study was to examine whether decitabine priming prior to low-dose chemotherapeutic regimens could improve outcomes in patients with myelodysplastic syndromes—refractory anemia with excess of bl...

Li Ye, Yanling Ren, ** Zhou, Chen Mei… in Journal of Cancer Research and Clinical On… (2017)

Article

Portal hypertension as the initial manifestation of POEMS syndrome: a case report

Portal hypertension has a broad differential diagnosis. POEMS syndrome is an uncommon cause of it. POEMS syndrome is a rare disease involving multiple organs. In differential diagnosis of portal hypertension, ...

Lina Wu, Yue Li, Fang Yao, Chongmei Lu, Jian Li, Weixun Zhou… in BMC Hematology (2017)

Article

Overexpression of CIP2A is associated with poor prognosis in multiple myeloma

Cancerous inhibitor of protein phosphatase 2A (CIP2A), an endogenous protein phosphatase 2A (PP2A) inhibitor, has been identified as an oncoprotein in promoting cancer initiation and progression of several typ...

Xuewen Liu, Wei Cao, Shanshan Qin, Te Zhang… in Signal Transduction and Targeted Therapy (2017)

Article

DNA methylation profile is associated with the osteogenic potential of three distinct human odontogenic stem cells

Among the various sources of human autologous stem cells, stem cells isolated from dental tissues exhibit excellent properties in tissue engineering and regenerative medicine. However, the distinct potential o...

Tingting Ai, Jieni Zhang, Xuedong Wang… in Signal Transduction and Targeted Therapy (2018)

Article

Detection of PRMT1 inhibitors with stopped flow fluorescence

Protein arginine methyltransferases (PRMTs) are crucial epigenetic regulators in eukaryotic organisms that serve as histone writers for chromatin remodeling. PRMTs also methylate a variety of non-histone prote...

Kun Qian, Hao Hu, Hui Xu, Y George Zheng in Signal Transduction and Targeted Therapy (2018)

Article

Increased mtDNA copy number promotes cancer progression by enhancing mitochondrial oxidative phosphorylation in microsatellite-stable colorectal cancer

Colorectal cancer is one of the leading causes of cancer death worldwide. According to global genomic status, colorectal cancer can be classified into two main types: microsatellite-stable and microsatellite-i...

**acheng Sun, Lei Zhan, Yibing Chen, Gang Wang… in Signal Transduction and Targeted Therapy (2018)

Article

Loss of mdig expression enhances DNA and histone methylation and metastasis of aggressive breast cancer

We previously reported that expression of an environmentally induced gene, mineral dust-induced gene (mdig), predicts overall survival in breast cancer patients. In the present report, we further demonstrate the ...

Chitra Thakur, Bailing Chen, Lingzhi Li… in Signal Transduction and Targeted Therapy (2018)

Article

Jumonji domain-containing 6 (JMJD6) identified as a potential therapeutic target in ovarian cancer

Jumonji domain-containing 6 (JMJD6) is a candidate gene associated with tumorigenesis, and JMJD6 overexpression predicts poor differentiation and unfavorable survival in some cancers. However, there are no stu...

Heng Zheng, Yan Tie, Zhen Fang, … in Signal Transduction and Targeted Therapy (2019)

Article

Author Correction: A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Hongwei Tian, Gang Shi, Qin Wang, Yiming Li… in Signal Transduction and Targeted Therapy (2019)

Article

Dual inhibition of CDK4 and FYN leads to selective cell death in KRAS-mutant colorectal cancer

Yan Wang, Rongjie Lin, Huan Ling, Yuan Ke… in Signal Transduction and Targeted Therapy (2019)

Article

Do persons with chronic myeloid leukaemia have normal or near normal survival?

Tomas Radivoyevitch, Davis Weaver, Brian Hobbs, Jaroslaw P. Maciejewski… in Leukemia (2020)

Article

YARS as an oncogenic protein that promotes gastric cancer progression through activating PI3K-Akt signaling

Members of the aaRS (aminoacyl-tRNA synthetase) family are proteins controlling the aminoacylation process, in which YARS (tyrosyl-tRNA synthetase) catalyzes the binding of tyrosine to its cognate tRNA and pla...

Cheng Zhang, **aoting Lin, Qian Zhao… in Journal of Cancer Research and Clinical On… (2020)

Article

Treatment Patterns and Economic Burden by Lines of Therapy Among Patients with Advanced Hepatocellular Carcinoma Treated with Systemic Cancer Therapy

This study examined clinical and economic outcomes among patients with advanced hepatocellular carcinoma (HCC) treated with systemic agents by line of therapy.

Machaon M. Bonafede, Beata Korytowsky, Prianka Singh… in Journal of Gastrointestinal Cancer (2020)

Article

Annotation and cluster analysis of long noncoding RNA linked to male sex and estrogen in cancers

The sex difference in cancer occurrence is a consistent finding in cancer epidemiology. Several solid tumors, including lung cancer, colorectal cancer, hepatic carcinoma, and renal carcinoma, are generally mor...

Shou** Liu, Weiwei Lai, Ying Shi, Na Liu, Lianlian Ouyang… in npj Precision Oncology (2020)

Article

Cancer-associated histone mutation H2BG53D disrupts DNA–histone octamer interaction and promotes oncogenic phenotypes

Yi Ching Esther Wan, Tsz Chui Sophia Leung… in Signal Transduction and Targeted Therapy (2020)