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  1. No Access

    Article

    MiR-4763-3p accelerates lipopolysaccharide-induced cardiomyocyte apoptosis and inflammatory response by targeting IL10RA

    In order to investigate miR-4763-3p and associated genes’ roles in myocarditis, AC16 cell line was divided into LPS + miR-4763-3p inhibitor, LPS + NC inhibitor, LPS + miR-4763-3p inhibitor + si-IL10RA and NC g...

    Lei Yang, Qian Dai, **aoming Bao, Wang Li, Jie Liu in Cytotechnology (2024)

  2. No Access

    Article

    Study on the mechanism of CXCL12/CXCR4-axis-mediated upregulation of IL-8 and IL-6 on the biological function of acute T lymphocyte leukaemia cells

    Blocking the CXCL12/CXCR4 axis can alter the biological functions of leukaemia cells. We hypothesise that interleukin (IL)-8 and IL-6 play an important role in this process. To test this hypothesis, we establi...

    Li** Zhou, Hui Zhao, Chao Zhang, Zhe Chen, Dong Li, Guanglei Qian in Cytotechnology (2024)

  3. No Access

    Article

    Exosome-mediated circGMPS facilitates the development of gastric cancer cells through miR-144-3p/PUM1

    In recent years, gastric cancer (GC) is still one of the major public health burdens in the world. It is reported that exosome circular RNA (circRNA) is involved in the GC progression. However, the function an...

    Yuexin Zhang, Wenrui **e, Wenhong Zheng, **aoying Qian, Chengwei Deng in Cytotechnology (2024)

  4. Article

    Retraction Note to: Lupeol induces apoptosis and inhibits invasion in gallbladder carcinoma GBC-SD cells by suppression of EGFR/MMP-9 signaling pathway

    Yan Liu, Tingting Bi, Genhai Shen, Zhimin Li, Guoliang Wu, Zheng Wang… in Cytotechnology (2022)

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  5. No Access

    Article

    Acetyl l-carnitine protects adipose-derived stem cells against serum-starvation: regulation on the network composed of reactive oxygen species, autophagy, apoptosis and senescence

    Adipose-derived stem cells (ADSCs) play an important role in cell therapy and regenerative medicine. However, local nutritional deficiency often limits therapeutical effect of the transplanted cells. Acetyl l-car...

    Tianyun Pan, Yao Qian, Tian Li, Zikai Zhang, Yucang He, **g** Wang… in Cytotechnology (2022)

  6. No Access

    Article

    Substrate coated with autologous decellularized extracellular matrix facilitates in vitro spreading of spheroid from adipose-derived stem cells through regulating ERK1/2-MMP2/9 pathway

    Adipose-derived stem cells (ADSCs) are easily available and play an important role in regenerative medicine. In recent years, Cell spheroid models have been in the spotlight because of their various advantages...

    Yao Qian, **aofang Yu, Tianyun Pan, Tian Li, Zikai Zhang, Xuling Lv… in Cytotechnology (2021)

  7. No Access

    Article

    The cell yields and biological characteristics of stromal/stem cells from lipoaspirate with different digestion loading ratio

    Effective harvesting procedure for adipose tissue is demanded by the affordable Good Manufacturing Practice-Compliant Production of clinical-grade adipose tissue-derived stem cells (hADSCs). Enzymatic digestio...

    Zifei Li, Dali Mu, Chunjun Liu, Minqiang **n, Su Fu, Shangshan Li, Jun Qi… in Cytotechnology (2020)

  8. No Access

    Article

    Combination of temperature shift and hydrolysate addition regulates anti-IgE monoclonal antibody charge heterogeneity in Chinese hamster ovary cell fed-batch culture

    Charge heterogeneity has been broadly studied as a critical quality attribute during monoclonal antibody (mAb) production that may subsequently affect product stability and biopotency. However, the charge vari...

    Chen Zheng, Chao Zhuang, **yan Qin, Yantian Chen, Qiang Fu, Hui Qian… in Cytotechnology (2018)

  9. No Access

    Article

    Analysis of toxicity effects of Di-(2-ethylhexyl) phthalate exposure on human bronchial epithelial 16HBE cells

    Recent studies have indicated that Di-(2-ethylhexyl) phthalate (DEHP), the most commonly used plasticizer in daily-life products, could be dispersed in indoor air and induce human exposure via inhalation. DEHP...

    Yue Ma, Yinsheng Guo, Shuang Wu, Ziquan Lv, Qian Zhang, **ng **e… in Cytotechnology (2018)

  10. No Access

    Article

    Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway

    Oxymatrine extracted from Sophora flavescens Ait as a natural polyphenolic phytochemical has been demonstrated to exhibit anti-tumor effects on various cancers, including Gallbladder carcinoma (GBC). However, ...

    Liqiang Qian, **aqin Li, Penghui Ye, Gang Wang, Wei Dai, Yan Liu… in Cytotechnology (2018)

  11. No Access

    Article

    Glioma targeting peptide in combination with the P53 C terminus inhibits glioma cell proliferation in vitro

    Glioma is a prevalent malignant primary brain tumor in adults, the treatment for which remains a challenge due to its high infiltration and recurrence. Hence, treatments that lead to the suppression of glioma ...

    Dan Wang, Meihua Guo, Jiawen Yu, **nying Wang, Qian Zhang, Xu Yang… in Cytotechnology (2018)

  12. No Access

    Article

    Development and characterization of monoclonal antibody against human IL-37b

    IL-37 has been described as a natural inhibitor of immune responses. Monoclonal antibody (mAb) against human IL-37b with high affinity and specificity can serve as a molecular probe to detect IL-37 and study I...

    Yu-Chi Gao, Yan Jia, De-Qian **ao, **n Wang, You-Chao Dai, Shi-Yan Yu… in Cytotechnology (2017)

  13. No Access

    Article

    Osteoprotegerin exposure at different stages of osteoclastogenesis differentially affects osteoclast formation and function

    This study aimed to investigate the effects of osteoprotegerin (OPG), a decoy receptor for receptor activator for nuclear factor κB ligand (RANKL), during the various stages of osteoclast differentiation, and ...

    Hongyan Zhao, Jianhong Gu, Nannan Dai, Qian Gao, Dong Wang, Ruilong Song… in Cytotechnology (2016)

  14. No Access

    Article

    Fluorescent labeling for clonal selection of Marc 145 cells secreting high levels of recombinant protein PBD-1

    Despite the powerful impact gene expression markers like the green fluorescent protein (GFP) or enhanced GFP (EGFP) exert on linking the expression of recombinant protein for selection of high producers in rec...

    Hai-Jun Huang, **a Peng, Bing Deng, Cong Huang, Jie Li, Yun-Guo Qian… in Cytotechnology (2016)

  15. No Access

    Article

    Atoh7 promotes retinal Müller cell differentiation into retinal ganglion cells

    Glaucoma is one of the leading eye diseases due to the death of retinal ganglion cells. Increasing evidence suggests that retinal Müller cells exhibit the characteristics of retinal progenitor cells and can di...

    Wei-tao Song, Qi Zeng, **ao-bo **a, Kun **a, Qian Pan in Cytotechnology (2016)

  16. No Access

    Article

    RETRACTED ARTICLE: Lupeol induces apoptosis and inhibits invasion in gallbladder carcinoma GBC-SD cells by suppression of EGFR/MMP-9 signaling pathway

    The cytostatic drug from fruits and other plant derived products have acted as a chemotherapeutic agent used in treatment of a wide variety of cancers. Lupeol, a dietary triterpene, present in many fruits and ...

    Yan Liu, Tingting Bi, Genhai Shen, Zhimin Li, Guoliang Wu, Zheng Wang… in Cytotechnology (2016)

  17. No Access

    Article

    VEGF165 expressing bone marrow mesenchymal stem cells differentiate into hepatocytes under HGF and EGF induction in vitro

    A short half-life and low levels of growth factors in an injured microenvironment necessitates the sustainable delivery of growth factors and stem cells to augment the regeneration of injured tissues. Our aim ...

    Yan Tan, En-hua **ao, Li-zhi **ao, You-hong Yuan, Cong Ma… in Cytotechnology (2012)

  18. No Access

    Article

    A rapid fluorescent screening method for cellular sensitivity to anti-cancer compound

    The tetrazolium salts (MTT, XTT, MTS, WST) based colorimetric assay or resazurin based fluorimetric assay are currently typical methods for cell sensitivity determination to anticancer compounds. We presented ...

    Wenwei Mao, **nlin Chen, Tian Yang, Yu Yin, Mei Ge, Minyu Luo… in Cytotechnology (2012)

  19. No Access

    Article

    Establishment, characterization and immortalization of a fibroblast cell line from the Chinese red belly toad Bombina maxima skin

    The skin of the amphibian Bombina maxima is rich in biologically active proteins and peptides, most of which have mammalian analogues. The physiological functions of most of the mammalian analogues are still unkn...

    Yang **ang, Qian Gao, Weiting Su, Lin Zeng, **huan Wang, Yi Hu… in Cytotechnology (2012)

  20. No Access

    Article

    On-line monitoring of oxygen in Tubespin, a novel, small-scale disposable bioreactor

    A novel, optical sensor was fixed in a new type of disposable bioreactor, Tubespin, for the on-line (real-time) monitoring of dissolved oxygen concentrations during cell culture. The cell density, viability an...

    Kui **e, **ao-Wei Zhang, Li Huang, Yi-Ting Wang, Yun Lei, **g Rong… in Cytotechnology (2011)

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