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Article
Open AccessAnalysis of allergen components and identification of bioactivity of HSP70 in pollen of Populus deltoides
Allergies caused by pollen from Populus deltoides are common, but the allergic components are still unclear.
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Article
Open AccessExposure to hypoxia causes stress erythropoiesis and downregulates immune response genes in spleen of mice
The spleen is the largest secondary lymphoid organ and the main site where stress erythropoiesis occurs. It is known that hypoxia triggers the expansion of erythroid progenitors; however, its effects on spleni...
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Article
Open AccessRead-Split-Run: an improved bioinformatics pipeline for identification of genome-wide non-canonical spliced regions using RNA-Seq data
Most existing tools for detecting next-generation sequencing-based splicing events focus on generic splicing events. Consequently, special types of non-canonical splicing events of short mRNA regions (IRE1α ta...
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Article
Open AccessStudies of genetic variability of the hepatocyte nuclear factor-1α gene in an Indian maturity-onset diabetes of the young family
Maturity-onset diabetes of the young (MODY), one of the specific types of diabetes mellitus, is a monogenetic disorder characterized by an autosomal dominant (AD) inheritance and β-cell dysfunction. To study a...
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Article
Open AccessExceptionally high cumulative percentage of NUMTs originating from linear mitochondrial DNA molecules in the Hydra magnipapillata genome
In contrast to most animal genomes, mitochondrial genomes in species belonging to the phylum Cnidaria show distinct variations in genome structure, including the mtDNA structure (linear or circular) and the pr...
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Article
Open AccessTranscriptomic and phylogenetic analysis of Culex pipiens quinquefasciatus for three detoxification gene families
The genomes of three major mosquito vectors of human diseases, Anopheles gambiae, Aedes aegypti, and Culex pipiens quinquefasciatus, have been previously sequenced. C. p. quinquefasciatus has the largest number o...