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Open AccessMarked variations in gut microbial diversity, functions, and disease risk between wild and captive alpine musk deer
Maintaining a healthy status is crucial for the successful captive breeding of endangered alpine musk deer (Moschus chrysogaster, AMD), and captive breeding programs are beneficial to the ex-situ conservation and...
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Article
PCSK9 Inhibition Regulates Infarction-Induced Cardiac Myofibroblast Transdifferentiation via Notch1 Signaling
Increasing evidence suggests that PCSK9 inhibition protects cardiomyocytes against ischemia-reperfusion injury after myocardial infarction. However, it is not clear whether PCSK9 inhibitor (PCSK9i) affects car...
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Article
Open AccessComparative analysis of gut microbial composition and potential functions in captive forest and alpine musk deer
Gut microbiota forms a unique microecosystem and performs various irreplaceable metabolic functions for ruminants. The gut microbiota is important for host health and provides new insight into endangered speci...
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Article
Retraction Note: DNA-guided genome editing using the Natronobacterium gregoryi Argonaute
Nat. Biotechnol. 34, 768–773 (2016); published online 2 May 2016; addendum published after print 28 November 2016; retracted 26 July 2017; 10.1038/nbt.3547 We are retracting our study because of the continued ...
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Addendum: Editorial Expression of Concern: DNA-guided genome editing using the Natronobacterium gregoryi Argonaute
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Article
DNA-guided genome editing using the Natronobacterium gregoryi Argonaute
Genome editing guided by a short single-stranded DNA is achieved with a nuclease from an archaebacterium.
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Article
Ameliorating Effects of Combined Curcumin and Desferrioxamine on 6-OHDA-Induced Rat Mode of Parkinson’s Disease
The catecholaminergic neurotoxin 6-hydroxydopamine has been widely used to mimic the lesions in dopaminergic neurons to develop Parkinson’s disease. The present study was aimed to evaluate the combined treatm...
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Article
Analysis of genomic characters reveals that four distinct gene clusters are correlated with different functions in Burkholderia cenocepacia AU 1054
Possessing three circular chromosomes is a distinct genomic characteristic of Burkholderia cenocepacia AU 1054, a clinically important pathogen in cystic fibrosis. In this study, base composition, codon usage and...
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Article
Biodegradation of Leonardite by an Alkali-producing bacterial community and characterization of the degraded products
In this study, three bacterial communities were obtained from 12 Leonardite samples with the aim of identifying a clean, effective, and economic technique for the dissolution of Leonardite, a type of low-grade...
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Article
Expression of glr gene encoding glutamate racemase in Bacillus licheniformis WX-02 and its regulatory effects on synthesis of poly-γ-glutamic acid
The glr gene, which encodes glutamate racemase involved in the conversion of l-glutamic acid to its D-isomer, was cloned and expressed in Bacillus licheniformis WX-02. Overexpression of the glr gene not only incr...