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  1. No Access

    Article

    Efficacy of the association of lenalidomide to erythropoiesis-stimulating agents in del (5q) MDS patients refractory to single-agent lenalidomide

    S Park, D Vassilieff, V Bardet, F Viguié, F Dreyfus in Leukemia (2010)

  2. No Access

    Article

    PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML

    The phosphatidylinositol 3-kinase (PI3K)/Akt and mammalian target of rapamycin complex 1 (mTORC1) signaling pathways are frequently activated in acute myelogenous leukemia (AML). mTORC1 inhibition with RAD001 ...

    S Park, N Chapuis, V Bardet, J Tamburini, N Gallay, L Willems, Z A Knight… in Leukemia (2008)

  3. No Access

    Article

    TRAF4 overexpression is a common characteristic of human carcinomas

    Tumor necrosis factor receptor (TNFR) associated factor 4 (TRAF4) was initially identified as a gene amplified and overexpressed in breast carcinomas. Our aim was to evaluate whether TRAF4 protein overexpressi...

    S Camilleri-Broët, I Cremer, B Marmey, E Comperat, F Viguié, J Audouin, M-C Rio… in Oncogene (2007)

  4. No Access

    Article

    Common 4q24 deletion in four cases of hematopoietic malignancy: early stem cell involvement?

    We determined bone marrow karyotype at diagnosis in four female acute myeloid leukemia (AML) or myelodysplasia patients, aged between 52 and 56 years. In each case, we observed chromosome rearrangement involvi...

    F Viguié, A Aboura, D Bouscary, S Ramond, A Delmer, G Tachdjian, J P Marie… in Leukemia (2005)

  5. No Access

    Article

    Report of 34 patients with clonal chromosomal abnormalities in Philadelphia-negative cells during imatinib treatment of Philadelphia-positive chronic myeloid leukemia

    Imatinib mesylate (Gleevec®), an inhibitor of the BCR-ABL tyrosine kinase, was introduced recently into the therapy of chronic myeloid leukemia (CML). Several cases of emergence of clonal chromosomal abnormalitie...

    C Terre, V Eclache, P Rousselot, M Imbert, C Charrin, C Gervais… in Leukemia (2004)

  6. No Access

    Article

    Pure red cell aplasia associated with myelodysplastic syndromes

    S Park, A Merlat, M Guesnu, F Picard, F Viguié, D Vassilieff, F Dreyfus in Leukemia (2000)

  7. No Access

    Article

    Multidrug resistance gene expression in acute myeloid leukemia: Major prognosis significance for in vivo drug resistance to induction treatment

     The clinical significance of the multidrug resistance (MDR 1) gene phenotype was investigated in newly diagnosed AML and was compared with other clinical and biological prognostic factors in patients who receive...

    M. Hunault, D. Zhou, A. Delmer, S. Ramond, F. Viguié, M. Cadiou… in Annals of Hematology (1997)