38 Result(s)
within
Article
Ewout J Hoorn
-
Article
Dietary sodium restriction prevents vascular endothelial growth factor inhibitor-induced hypertension
Vascular endothelial growth factor inhibitors (VEGFIs) are effective anticancer agents which often induce hypertension. VEGFI-induced hypertension is sodium-sensitive in animal studies. Therefore, the efficacy...
-
Article
Correction to: Outcomes of parathyroidectomy versus calcimimetics for secondary hyperparathyroidism and kidney transplantation: a propensity-matched analysis
An Erratum to this paper has been published: https://doi.org/10.1007/s00423-020-02046-z
-
Article
Comment to “Recommendation on an updated standardization of serum magnesium reference ranges”
-
Article
Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease
Adult kidney organoids have been described as strictly tubular epithelia and termed tubuloids. While the cellular origin of tubuloids has remained elusive, here we report that they originate from a distinct CD24+
-
Article
Open AccessPotassium and the kidney: a reciprocal relationship with clinical relevance
By controlling urinary potassium excretion, the kidneys play a key role in maintaining whole-body potassium homeostasis. Conversely, low urinary potassium excretion (as a proxy for insufficient dietary intake)...
-
Article
Salt substitution: opportunities and challenges for nephrology
Salt substitution — the partial replacement of sodium with potassium in table salt — is emerging as a powerful public health strategy to reduce hypertension and related diseases. Here, we explore whether salt ...
-
Article
Open AccessPersonalized screening intervals for kidney function in patients with chronic heart failure: a modeling study
High mortality and rehospitalization rates demonstrate that improving risk assessment in heart failure patients remains challenging. Individual temporal evolution of kidney biomarkers is associated with poor c...
-
Article
Open AccessEffect of sodium bicarbonate supplementation on the renin-angiotensin system in patients with chronic kidney disease and acidosis: a randomized clinical trial
Acidosis-induced kidney injury is mediated by the intrarenal renin-angiotensin system, for which urinary renin is a potential marker. Therefore, we hypothesized that sodium bicarbonate supplementation reduces ...
-
Article
Outcomes of parathyroidectomy versus calcimimetics for secondary hyperparathyroidism and kidney transplantation: a propensity-matched analysis
Calcimimetics are currently indicated for severe secondary hyperparathyroidism (SHPT). However, the role of parathyroidectomy (PTX) for these patients is still under debate, and its impact on subsequent kidney...
-
Article
Open AccessLong-term prognosis after kidney donation: a propensity score matched comparison of living donors and non-donors from two population cohorts
Live donor nephrectomy is a safe procedure. However, long-term donor prognosis is debated, necessitating high-quality studies.
-
Article
Open AccessCorrection to: Intravenous fluids: balancing solutions
In Table 3 on Page 486 the term osmolality should have read osmolarity.
-
Article
Open AccessTiming of Parathyroidectomy Does Not Influence Renal Function After Kidney Transplantation
Parathyroidectomy (PTx) is the treatment of choice for end-stage renal disease (ESRD) patients with therapy-resistant hyperparathyroidism (HPT). The optimal timing of PTx for ESRD-related HPT—before or after k...
-
Article
A preliminary survey of practice patterns across several European kidney stone centers and a call for action in develo** shared practice
Currently an evidence-based approach to nephrolithiasis is hampered by a lack of randomized controlled trials. Thus, there is a need for common platforms for data sharing and recruitment of patients to interve...
-
Article
Open AccessSafety and efficacy of subtotal or total parathyroidectomy for patients with secondary or tertiary hyperparathyroidism in four academic centers in the Netherlands
Hyperparathyroidism (HPT) is a common abnormality in patients with end-stage renal disease (ESRD). Since the introduction of cinacalcet in 2004, a shift from surgery toward predominantly medical treatment has ...
-
Article
Prostaglandins in thiazide-induced hyponatraemia: do they hold water?
Thiazide diuretics lower blood pressure and cardiovascular risk but can cause severe hyponatraemia. Researchers now demonstrate that thiazide-induced hyponatraemia is associated with a genetic variant in a dis...
-
Article
GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes
The incretins glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are gut-derived hormones that potentiate insulin secretion...
-
Article
Open AccessIntravenous fluids: balancing solutions
The topic of intravenous (IV) fluids may be regarded as “reverse nephrology”, because nephrologists usually treat to remove fluids rather than to infuse them. However, because nephrology is deeply rooted in fl...
-
Article
Open AccessSerum magnesium and the risk of prediabetes: a population-based cohort study
Previous studies have found an association between serum magnesium and incident diabetes; however, this association may be due to reverse causation, whereby diabetes may induce urinary magnesium loss. In contr...
-
Article
Open AccessFrom ARB to ARNI in Cardiovascular Control
Coexistence of hypertension, diabetes mellitus and chronic kidney disease synergistically aggravates the risk of cardiovascular and renal morbidity and mortality. These high-risk, multi-morbid patient populati...
-
Article
Open AccessNeutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury
Acute kidney injury (AKI) is a frequently encountered complication of imported Plasmodium falciparum infection. Markers of structural kidney damage have been found to detect AKI earlier than serum creatinine-base...
