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    Article

    Association between endometriosis and gynecological cancers: a critical review of the literature

    Endometriosis is one of the most common benign gynecological diseases with an occurrence approximately 10% in reproductive age. Endometriosis has been proposed as a possible precursor of certain ovarian carcin...

    Dimitrios Rafail Kalaitzopoulos in Archives of Gynecology and Obstetrics (2020)

  2. Article

    Open Access

    Doxycycline reduces MMP-2 activity and inhibits invasion of 12Z epithelial endometriotic cells as well as MMP-2 and -9 activity in primary endometriotic stromal cells in vitro

    Matrix metalloproteinases (MMPs), especially the gelatinases MMP-2 and MMP-9, play a crucial role in the pathogenesis of endometriosis by enabling invasion. Doxycycline is a well-tolerated antibiotic and a pot...

    Eleftherios P. Samartzis, Daniel Fink in Reproductive Biology and Endocrinology (2019)

  3. Article

    Open Access

    Expression of the G protein-coupled estrogen receptor (GPER) in endometriosis: a tissue microarray study

    The G protein-coupled estrogen receptor (GPER) is thought to be involved in non-genomic estrogen responses as well as processes such as cell proliferation and migration. In this study, we analyzed GPER express...

    Nicolas Samartzis, Eleftherios P Samartzis in Reproductive Biology and Endocrinology (2012)