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Open AccessA meta-analysis of gene expression quantitative trait loci in brain
Current catalogs of brain expression quantitative trait loci (eQTL) are incomplete and the findings do not replicate well across studies. All existing cortical eQTL studies are small and emphasize the need for...
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Article
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
We conducted data-mining analyses using the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) and molecular genetics of schizophrenia genome-wide association study supported by the genetic as...
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Article
Erratum: Genomewide association for schizophrenia in the CATIE study: results of stage 1
Correction to: Molecular Psychiatry (2008) 13, 570â584; doi: 10.1038/mp.2008.25 For technical reasons, Supplementary Tables 2, 3 and 4 were not published online. They now appear online at www.nature.com/mp.
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Article
Genomewide association for schizophrenia in the CATIE study: results of stage 1
Little is known for certain about the genetics of schizophrenia. The advent of genomewide association has been widely anticipated as a promising means to identify reproducible DNA sequence variation associated...
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Article
A region of 35âkb containing the trace amine associate receptor 6 (TAAR6) gene is associated with schizophrenia in the Irish study of high-density schizophrenia families
The TAAR6 gene has been previously associated with schizophrenia in 192 pedigrees of European and African ancestry. To replicate these findings we performed an association study of TAAR6 in 265 pedigrees of the I...
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Article
Interleukin 3 and schizophrenia: the impact of sex and family history
Chromosome 5q21â33 has been implicated in harboring risk genes for schizophrenia. In this paper, we report evidence that multiple single nucleotide polymorphisms in and around interleukin 3 (IL3) are associated w...
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Article
Alcohol dependence is associated with the ZNF699 gene, a human locus related to Drosophila hangover, in the Irish affected sib pair study of alcohol dependence (IASPSAD) sample
Because tolerance is an important aspect of alcohol dependence (AD) in humans, recent evidence showing that the Drosophila gene hang is critically involved in the development of alcohol tolerance in the fly sugge...