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Article
Involvement of transcription factor activator protein-2α in doxazosin-induced HeLa cell apoptosis
To investigate the pro-apoptotic effects of α-1-adrenergic inhibitor doxazosin in HeLa cells and the potential involvement of transcription factor activator protein-2α (AP-2α) in doxazosin-induced apoptosis.
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Article
Open AccessCu2ZnSnSe4 nanocrystals capped with S2− by ligand exchange: utilizing energy level alignment for efficiently reducing carrier rec ombination
In this work, we employed a convenient one-step synthesis method for synthesizing Cu2ZnSnSe4 (CZTSe) nanocrystals (NCs) in an excess selenium environment. This excess selenium situation enhanced the reaction of m...
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Article
Open AccessSuper-resolution imaging and tracking of protein–protein interactions in sub-diffraction cellular space
Imaging the location and dynamics of individual interacting protein pairs is essential but often difficult because of the fluorescent background from other paired and non-paired molecules, particularly in the ...
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Article
Open AccessSerotonergic mechanism of the relieving effect of bee venom acupuncture on oxaliplatin-induced neuropathic cold allodynia in rats
Oxaliplatin, an important chemotherapy drug for advanced colorectal cancer, often induces peripheral neuropathy, especially cold allodynia. Our previous study showed that bee venom acupuncture (BVA), which has...
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Article
Open AccessEffectiveness and safety of Glucosamine, chondroitin, the two in combination, or celecoxib in the treatment of osteoarthritis of the knee
This study aimed to investigate the effectiveness and safety of glucosamine, chondroitin, the two in combination, or celecoxib in the treatment of knee osteoarthritis (OA). PubMed, Embase and Cochrane Library ...
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Article
Open AccessAntibacterial activity of a modified unfilled resin containing a novel polymerizable quaternary ammonium salt MAE-HB
Resins with strong and long-lasting antibacterial properties are critical for the prevention of secondary dental caries. In this study, we evaluated the antibacterial effect and the underlying mechanism of act...
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Open AccessAnalgesic effect and safety of single-dose intra-articular magnesium after arthroscopic surgery: a systematic review and meta-analysis
To examine the analgesic effect and safety of single-dose intra-articular (IA) magnesium (Mg) after arthroscopic surgery. Pubmed, Embase and Cochrane library were searched through in January 2016. Eight RCTs a...
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Article
Open AccessDose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis
The aim was to assess serum magnesium levels in relation to prevalence of knee chondrocalcinosis in two population-based Chinese studies.
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Article
Open AccessAssociation between metabolic syndrome and knee osteoarthritis: a cross-sectional study
Osteoarthritis (OA) is the most prevalent chronic joint disease in China. The aim of this study was to examine the association between metabolic syndrome (MetS) and knee OA in a population-based Chinese study.
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Article
Open AccessTotal synthesis of cyrneines A–B and glaucopine C
The cyrneine diterpenoids represent a structurally intriguing subfamily of cyathane diterpenoids and could significantly induce neurite outgrowth. Therefore, the efficient synthesis of these natural products i...
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Article
Open AccessArsenic trioxide inhibits liver cancer stem cells and metastasis by targeting SRF/MCM7 complex
Hepatocellular carcinoma (HCC) has a high mortality rate due to the lack of effective treatments and drugs. Arsenic trioxide (ATO), which has been proved to successfully treat acute promyelocytic leukemia (APL...
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Article
Open AccessComparison of the chemical and micromechanical properties of Larix spp. after eco-friendly heat treatments measured by in situ nanoindentation
Heat treatment is a green, environmentally friendly and mild pyrolysis process that improves the dimensional stability and durability of wood. In this study, Larix spp. Samples were heated at 180 °C and 210 °C fo...
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Article
Open AccessEnantioselective three-component aminomethylation of α-diazo ketones with alcohols and 1,3,5-triazines
Enantioselective α-aminomethylation of carbonyl compounds constitutes a powerful protocol for introducing aminomethyl groups to simple organic molecules. However, current strategies rely on nucleophile-based enan...
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Article
Open AccessOpposing biological functions of the cytoplasm and nucleus DAXX modified by SUMO-2/3 in gastric cancer
Death domain-associated protein (DAXX) is a complex biological multifunctional protein and is involved in the tumorigenesis and progression of multiple cancers. The accumulation of DAXX in the nucleus is a com...
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Article
Open AccessBase level changes based on Basin Filling Modelling: a case study from the Paleocene Lishui Sag, East China Sea Basin
Estimation of base level changes in geological records is an important topic for petroleum geologists. Taking the Paleocene Upper Lingfeng Member of Lishui Sag as an example, this paper conducted a base level ...
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Article
Open AccessEvaluation of the therapeutic effect of high-flow nasal cannula oxygen therapy on patients with aspiration pneumonia accompanied by respiratory failure in the post-stroke sequelae stage
The aim of the present study was to evaluate the therapeutic effect of high-flow nasal cannula (HFNC) oxygen therapy on patients with aspiration pneumonia accompanied by respiratory failure in the post-stroke ...
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Article
Open AccessNonreciprocal charge transport up to room temperature in bulk Rashba semiconductor α-GeTe
Nonmagnetic Rashba systems with broken inversion symmetry are expected to exhibit nonreciprocal charge transport, a new paradigm of unidirectional magnetoresistance in the absence of ferromagnetic layer. So fa...
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Article
Open AccessQuantitative analysis of contrast enhanced spectral mammography grey value for early prediction of pathological response of breast cancer to neoadjuvant chemotherapy
A quantitative analysis of contrast-enhanced spectral mammography (CESM) enhancement was conducted for the early prediction of the pathological response after neoadjuvant chemotherapy (NAC). Retrospective anal...
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Open AccessBiochar-bacteria partnership based on microbially induced calcite precipitation improves Cd immobilization and soil function
Microbially induced calcite precipitation (MICP) technique utilizes ureolytic bacteria to decompose urea and generate carbonate ions for metal combination. MICP can remediate heavy metal (e.g., Cd) contaminate...
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Open AccessA CNN-LSTM-att hybrid model for classification and evaluation of growth status under drought and heat stress in chinese fir (Cunninghamia lanceolata)
Cunninghamia lanceolata (Chinese fir), is one of the most important timber trees in China. With the global warming, to develop new resistant varieties to drought or heat stress has become an essential task for br...