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  1. Article

    Open Access

    Development of a Serum-Based MicroRNA Signature for Early Detection of Pancreatic Cancer: A Multicenter Cohort Study

    A grim prognosis of pancreatic cancer (PCa) was attributed to the difficulty in early diagnosis of the disease.

    **g Huang, Ge Gao, Yang Ge, Jianzhou Liu, Hongtu Cui in Digestive Diseases and Sciences (2024)

  2. No Access

    Article

    Nintedanib Alleviates Chronic Pancreatitis by Inhibiting the Activation of Pancreatic Stellate Cells via the JAK/STAT3 and ERK1/2 Pathways

    Nintedanib (Ninte) has been approved for the treatment of pulmonary fibrosis, and whether it can ameliorate chronic pancreatitis (CP) is unknown.

    Chao Han, Li-Juan Wang, Zhi-Qi Dong, Peng-Yuan Wang in Digestive Diseases and Sciences (2023)

  3. No Access

    Article

    Concomitant Diseases and Co-contribution on Progression of Liver Stiffness in Patients with Hepatitis B Virus Infection

    The association between hepatitis B and concomitant diseases, such as fatty liver, T2DM, MetS, and Hp infection, remains unclear.

    Chang-Hai Liu, Wei Jiang, Dong-Bo Wu, Qing-Min Zeng in Digestive Diseases and Sciences (2023)

  4. No Access

    Article

    Auricular Vagus Nerve Stimulation Ameliorates Functional Dyspepsia with Depressive-Like Behavior and Inhibits the Hypothalamus–Pituitary–Adrenal Axis in a Rat Model

    The hypothalamus–pituitary–adrenal axis is the most important endocrine system to control irritability response. Functional dyspepsia (FD) is closely related to irritability. This study aimed to preliminarily ...

    Li-wei Hou, Ji-liang Fang, **-ling Zhang, Lei Wang in Digestive Diseases and Sciences (2022)

  5. No Access

    Article

    Hypoxic Hepatocellular Carcinoma Cells Acquire Arsenic Trioxide Resistance by Upregulating HIF-1α Expression

    Although arsenic trioxide (ATO) is used in the treatment of advanced hepatocellular carcinoma (HCC) in clinical trials, it is not satisfactory in terms of improving HCC patients’ overall survival. Intratumoral...

    Yaoting Chen, Huiqing Li, Dong Chen, **ongying Jiang in Digestive Diseases and Sciences (2022)

  6. No Access

    Article

    Hypertriglyceridemia Acute Pancreatitis: Animal Experiment Research

    In recent years, the number of acute pancreatitis cases caused by hypertriglyceridemia has increased gradually, which has caught the attention of the medical community. However, because the exact mechanism of ...

    Lu Wang, Ting Xu, Ruifeng Wang, **aobing Wang, Dong Wu in Digestive Diseases and Sciences (2022)

  7. No Access

    Article

    Role of eIF3C Overexpression in Predicting Prognosis of Intrahepatic Cholangiocarcinoma

    Elevated expression of eukaryotic initiation factor 3c (eIF3C) was recently uncovered to promote several types of cancer progression by inducing cell proliferation. Here, we aimed to assess the expression and ...

    Ya-** Xu, Ze-Ning Dong, Ying-Qun Zhou, Yu-Jie Zhao in Digestive Diseases and Sciences (2022)

  8. No Access

    Article

    Comparison of Scoring Systems in Predicting Severity and Prognosis of Hypertriglyceridemia-Induced Acute Pancreatitis

    In China, hyperlipidemia is the second major reason of acute pancreatitis.

    Man Li, **ao-kang **ng, Zhi-hua Lu, Feng Guo, Wei Su in Digestive Diseases and Sciences (2020)

  9. No Access

    Article

    GADD45G Interacts with E-cadherin to Suppress the Migration and Invasion of Esophageal Squamous Cell Carcinoma

    Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent cancers with poor prognosis. Metastasis is the leading cause of cancer-related deaths. The growth arrest and DNA damage-inducible 45 gamma...

    Tongtong Li, Lele Xu, **glei Teng, Yun** Ma in Digestive Diseases and Sciences (2020)

  10. No Access

    Article

    Effects of Photoperiod on Acetaminophen-Induced Hepatotoxicity in Mice

    Acetaminophen (APAP) is a clinically popular analgesic and antipyretic drug, but excessive APAP can cause fatal hepatotoxicity. Many factors affect the degree of APAP-induced liver injury. This study aimed to ...

    Jihong Lu, Hu Wang, Rumeng Zhang, Zhikang Wan, Hang Gao in Digestive Diseases and Sciences (2020)

  11. No Access

    Article

    A New Fully Covered Self-Expandable Metal Stent for the Treatment of Postsurgical Benign Biliary Strictures

    Endotherapy with plastic stent (PS) placement is the main modality for treating benign biliary strictures (BBSs). Fully covered self-expandable metal stents (FCSEMSs) are being increasingly used for BBS manage...

    Jun Wu, Dong-xun Zhou, Tian-tian Wang, Dao-jian Gao in Digestive Diseases and Sciences (2017)

  12. No Access

    Article

    Helicobacter pylori Infection Status Correlates with Serum Parameter Levels Responding to Multi-organ Functions

    Epidemiological studies have demonstrated the relationship between Helicobacter pylori infection and gastric and extra-gastric diseases. Therefore, H. pylori infection might be a “systemic” disease.

    Yuehua Gong, Wang Wei, Liu **gwei, Dong Nannan in Digestive Diseases and Sciences (2015)

  13. No Access

    Article

    Comparison Between Botulinum Injection and Removable Covered Self-Expanding Metal Stents for the Treatment of Achalasia

    Intrasphincteric injection of botulinum toxin (BTX) and removable self-expanding metal stents (SEMS) have both been used for the treatment of achalasia.

    **ao Bo Cai, Yan Miao Dai, **n Jian Wan, Yue Zeng in Digestive Diseases and Sciences (2013)

  14. No Access

    Article

    Neoadjuvant Chemoradiotherapy Could Improve Survival Outcomes for Esophageal Carcinoma: A Meta-Analysis

    The effectiveness of neoadjuvant chemoradiotherapy in patients with resectable esophageal carcinoma remains controversial.

    Dong-Bin Wang, Xun Zhang, Hong-Li Han, Yi-Jun Xu in Digestive Diseases and Sciences (2012)

  15. No Access

    Article

    The Expression of Protease-Activated Receptor 2 and 4 in the Colon of Irritable Bowel Syndrome Patients

    Irritable bowel syndrome (IBS) pathophysiology has not been fully understood. Abnormalities of serine proteases have been identified in IBS patients. In addition, protease-activated receptors (PAR) activation ...

    Ju-hui Zhao, Lei Dong, Hai-tao Shi, Zong-yan Wang in Digestive Diseases and Sciences (2012)

  16. No Access

    Article

    Hepatic Angiomyolipoma: A Clinical Experience in Diagnosis and Treatment

    Hepatic angiomyolipoma is a rare mesenchyme-derived neoplasm often misdiagnosed as hepatocellular carcinoma, and the treatment for it remains controversial.

    Jian-** Zeng, Jia-Hong Dong, Wen-Zhi Zhang, **g Wang in Digestive Diseases and Sciences (2010)

  17. No Access

    Article

    Long-Term Repopulation Effects of Donor BMDCs on Intestinal Epithelium

    Bone marrow-derived cells (BMDCs) have the ability to differentiate into intestinal epithelial cells after transplantation and participate in the regeneration process of damaged epithelium.

    Liu Dengqun, Wang Fengchao, Zou Zhongmin, Dong Shiwu in Digestive Diseases and Sciences (2010)

  18. No Access

    Article

    The Effectiveness of the Treatment of Octreotide on Chylous Ascites After Liver Cirrhosis

    Octreotide is a crucial drug used for treating patients with chylous ascites; however, there have been few reports related to octreotide that are being used in cirrhotic patients. Thus, this thesis is designe...

    Dong Xun Zhou, Hua Bang Zhou, Qing Wang, Shan Shan Zou in Digestive Diseases and Sciences (2009)