884 Result(s)

Article

Molecular cloning and characterization of the mouse Acdp gene family

We have recently cloned and characterized a novel gene family named ancient conserved domain protein (ACDP) in humans. To facilitate the functional study of this novel gene family, we have cloned and characterize...

Cong-Yi Wang, ** Yang, **g-Da Shi, Sharad Purohit, Dehuang Guo… in BMC Genomics (2004)

Article

Genomic compositions and phylogenetic analysis of Shigella boydii subgroup

Comparative Genomic Hybridization (CGH) microarray analysis was used to compare the genomic compositions of all eighteen Shigella boydii serotype representative strains. The results indicated the genomic “backbon...

**g Wang, **aobing Zhang, Jun** Peng, E. Yang, Wen Bin… in Science in China Series C (2006)

Article

Hypocrellin D, a Cytotoxic Fungal Pigment from Fruiting Bodies of the Ascomycete Shiraia bambusicola

A fungal pigment, hypocrellin D (1), together with three known perylenequinone derivatives hypocrellin A (2), B (3) and C (4), was isolated from the fruiting bodies of Shiraia bambusicola. Its structure was eluci...

Li-Zhen Fang, Chen Qing, Hong-Jun Shao, Yi-Dong Yang… in The Journal of Antibiotics (2006)

Article

Analysis of the dermatophyte Trichophyton rubrum expressed sequence tags

Dermatophytes are the primary causative agent of dermatophytoses, a disease that affects billions of individuals worldwide. Trichophyton rubrum is the most common of the superficial fungi. Although T. rubrum is a...

Lingling Wang, Li Ma, Wenchuan Leng, Tao Liu, Lu Yu, Jian Yang, Li Yang… in BMC Genomics (2006)

Article

A New Cadinane Sesquiterpene with Significant Anti-HIV-1 Activity from the Cultures of the Basidiomycete Tyromyces chioneus

A new cadinane sesquiterpene (4β,14-dihydroxy-6α,7βH-1(10)-cadinene, 1) was isolated from the cultures of the basidiomycete, Tyromyces chioneus. Its structure was established on the basis of spectral measurements...

Dong-Ze Liu, Fei Wang, Liu-Meng Yang, Yong-Tang Zheng… in The Journal of Antibiotics (2007)

Article

The Arabidopsis Spontaneous Cell Death1 gene, encoding a ζ-carotene desaturase essential for carotenoid biosynthesis, is involved in chloroplast development, photoprotection and retrograde signalling

Carotenoids, a class of natural pigments found in all photosynthetic organisms, are involved in a variety of physiological processes, including coloration, photoprotection, biosynthesis of abscisic acid (ABA) ...

Haili Dong, Yan Deng, **ye Mu, Qingtao Lu, Yiqin Wang, Yunyuan Xu… in Cell Research (2007)

Article

Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins

Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residue preferences have been widely used in man...

Qiwen Dong, **aolong Wang, Lei Lin, Yi Guan in BMC Bioinformatics (2007)

Article

Identification of genes differentially expressed during larval molting and metamorphosis of Helicoverpa armigera

Larval molting and metamorphosis are important physiological processes in the life cycle of the holometabolous insect. We used suppression subtractive hybridization (SSH) to identify genes differentially expre...

Du-Juan Dong, Hong-Juan He, Lian-Qin Chai, **ao-Juan Jiang… in BMC Developmental Biology (2007)

Article

Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice

Genes in the CCCH family encode zinc finger proteins containing the motif with three cysteines and one histidine residues. They have been known to play important roles in RNA processing as RNA-binding proteins...

Dong Wang, Yinghui Guo, Changai Wu, Guodong Yang, Yingying Li… in BMC Genomics (2008)

Article

Immunological dynamics in response to two anthrax vaccines in mice

In order to understand the variation of humoral and cellular immune responses to A16R live spore and AVA vaccine and to identify efficient immunological parameters for the early evaluation of post immunization...

** Lü, Rui He, Mei Dong, LiangYan Zhang… in Science in China Series C: Life Sciences (2008)

Article

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

Viral infection causes host cells to produce type I interferons (IFNs), which are critically involved in viral clearance. Previous studies have demonstrated that activation of the transcription factor interfer...

Min Zhang, Yang Tian, Rui-Peng Wang, Dong Gao, Yan Zhang, Fei-Ci Diao… in Cell Research (2008)

Article

Enhancement of memory function in aged mice by a novel derivative of xanomeline

Yihui Cui, Dong Wang, Wen Si, Wen Lv, Yan Niu, ** Lei, Yinhe Hu… in Cell Research (2008)

Article

Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis

The protein phosphatase 2Cs (PP2Cs) from various organisms have been implicated to act as negative modulators of protein kinase pathways involved in diverse environmental stress responses and developmental pro...

Tongtong Xue, Dong Wang, Shizhong Zhang, Juergen Ehlting, Fei Ni… in BMC Genomics (2008)

Article

A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic analysis

Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) are the most effective and accurate method...

Bin Liu, **aolong Wang, Lei Lin, Qiwen Dong, Xuan Wang in BMC Bioinformatics (2008)

Article

Proteomics, pathway array and signaling network-based medicine in cancer

Cancer is a multifaceted disease that results from dysregulated normal cellular signaling networks caused by genetic, genomic and epigenetic alterations at cell or tissue levels. Uncovering the underlying prot...

David Y Zhang, Fei Ye, Ling Gao, **aoliang Liu, **n Zhao, Yufang Che… in Cell Division (2009)

Article

Design, synthesis and antibacterial activity of a novel alkylide: 3-O-(3-aryl-propenyl)clarithromycin derivatives

A series of novel 3-O-(3-aryl-propenyl)clarithromycin derivatives were designed, synthesized and evaluated for their in vitro antibacterial activities. Regioselective allylation at 3-OH was efficiently achieved i...

Jian-Hua Liang, Yue-Ying Wang, Dan-Yang Zhu, Li-**g Dong… in The Journal of Antibiotics (2009)

Article

p28^GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity

It has been shown that oncoprotein p28^GANK, which is consistently overexpressed in human hepatocellular carcinoma (HCC), plays a critical role in tumorigenesis of HCC. However, the underlying mechanism remains un...

Rong-Yang Dai, Yao Chen, **g Fu, Li-Wei Dong, Yi-Bin Ren, Guang-Zhen Yang… in Cell Research (2009)

Article

Prediction of protein binding sites in protein structures using hidden Markov support vector machine

Predicting the binding sites between two interacting proteins provides important clues to the function of a protein. Recent research on protein binding site prediction has been mainly based on widely known mac...

Bin Liu, **aolong Wang, Lei Lin, Buzhou Tang, Qiwen Dong, Xuan Wang in BMC Bioinformatics (2009)

Article

DNA interaction networks: an information highway for regulated gene expression in the 3-dimentional space of the nucleus

Dong Wang, **ang-Dong Fu in Cell Research (2009)

Article

The Arabidopsis PARAQUAT RESISTANT2 gene encodes an S-nitrosoglutathione reductase that is a key regulator of cell death

Metabolism of S-nitrosoglutathione (GSNO), a major biologically active nitric oxide (NO) species, is catalyzed by the evolutionally conserved GSNO reductase (GSNOR). Previous studies showed that the Arabidopsis G...

Ruiqiang Chen, Shulan Sun, Chun Wang, Yansha Li, Yan Liang, Fengying An… in Cell Research (2009)