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Article

Targeted depletion of TRBV9⁺ T cells as immunotherapy in a patient with ankylosing spondylitis

Autoimmunity is intrinsically driven by memory T and B cell clones inappropriately targeted at self-antigens. Selective depletion or suppression of self-reactive T cells remains a holy grail of autoimmune ther...

Olga V. Britanova, Kseniia R. Lupyr, Dmitry B. Staroverov… in Nature Medicine (2023)