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  1. Article

    Open Access

    Assessing the perioperative outcomes of abdominal drain omission after robot-assisted partial nephrectomy

    The study aimed to evaluate the impact of abdominal drain placement (vs. omission) on perioperative outcomes of robot-assisted partial nephrectomy (RAPN), focusing on complications, time to canalization, deamb...

    Francesco Ditonno, Riccardo Bertolo, Alessandro Veccia in Scientific Reports (2024)

  2. No Access

    Article

    Tumor upgrading among very favorable intermediate-risk prostate cancer patients treated with robot-assisted radical prostatectomy: how can it impact the clinical course?

    We sought to investigate predictors of unfavorable tumor upgrading in very favorable intermediate-risk (IR) prostate cancer (PCa) patients treated with robot-assisted radical prostatectomy, in addition to eval...

    Antonio Benito Porcaro, Alberto Bianchi in International Urology and Nephrology (2024)

  3. Article

    Open Access

    Preoperative endogenous testosterone density predicts disease progression from localized impalpable prostate cancer presenting with PSA levels elevated up to 10 ng/mL

    To investigate endogenous testosterone density (ETD) predicting disease progression from clinically localized impalpable prostate cancer (PCa) presenting with prostate-specific antigen (PSA) levels elevated up...

    Antonio Benito Porcaro, Alberto Bianchi in International Urology and Nephrology (2023)

  4. Article

    Open Access

    Medium supplementation can influence the human ovarian cells in vitro

    Cells are an essential part of the triple principles of tissue engineering and a crucial component of the engineered ovary as they can induce angiogenesis, synthesize extracellular matrix and influence follicl...

    Arezoo Dadashzadeh, Saeid Moghassemi, Monika Grubliauskaité in Journal of Ovarian Research (2022)

  5. Article

    Open Access

    Advanced age portends poorer prognosis after radical prostatectomy: a single center experience

    Although advanced age doesn’t seem to impair oncological outcomes after robot-assisted radical prostatectomy (RARP), elderly patients have increased rates of prostate cancer (PCa) related deaths due to a highe...

    Antonio Benito Porcaro, Alberto Bianchi in Aging Clinical and Experimental Research (2022)

  6. Article

    Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis

    How metabolic pathways required for epidermal tissue growth and remodeling influence the ability of keratinocytes to survive stressful conditions is still largely unknown. The mechanistic target of rapamycin c...

    Beatrice Tassone, Stefania Saoncella, Francesco Neri in Cell Death & Differentiation (2017)

  7. Article

    Open Access

    RNAs competing for microRNAs mutually influence their fluctuations in a highly non-linear microRNA-dependent manner in single cells

    Distinct RNA species may compete for binding to microRNAs (miRNAs). This competition creates an indirect interaction between miRNA targets, which behave as miRNA sponges and eventually influence each other’s e...

    Carla Bosia, Francesco Sgrò, Laura Conti, Carlo Baldassi, Davide Brusa in Genome Biology (2017)

  8. Article

    Open Access

    iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells

    Doxorubicin is one of the few chemotherapeutic drugs able to exert both cytotoxic and pro-immunogenic effects against cancer cells. Following the drug administration, the intracellular protein calreticulin is ...

    Sara De Boo, Joanna Kopecka, Davide Brusa, Elena Gazzano, Lina Matera in Molecular Cancer (2009)

  9. Article

    Open Access

    Correlation between NK function and response to trastuzumab in metastatic breast cancer patients

    Trastuzumab is a monoclonal antibody selectively directed against Her2 and approved for the treatment of Her2 overexpressing breast cancer patients. Its proposed mechanisms of action include mediation of antib...

    Alessandra Beano, Elena Signorino, Andrea Evangelista in Journal of Translational Medicine (2008)