Skip to main content

2 Result(s)

within Article Remove this filter David Schrama Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

and

  1. Article

    Open Access

    Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma

    Merkel cell carcinoma (MCC) is a rare and aggressive, yet highly immunogenic skin cancer. The latter is due to its viral or UV-associated carcinogenesis. For tumor progression MCC has to escape the host’s immu...

    Cathrin Ritter, Kaiji Fan, Annette Paschen, Sine Reker Hardrup… in Scientific Reports (2017)

    Download PDF (8120 KB) View Article

  2. Article

    Open Access

    Reversal of epigenetic silencing of MHC class I chain-related protein A and B improves immune recognition of Merkel cell carcinoma

    Merkel cell carcinoma (MCC) is a virally associated cancer characterized by its aggressive behavior and strong immunogenicity. Both viral infection and malignant transformation induce expression of MHC class I...

    Cathrin Ritter, Kaiji Fan, Kelly G. Paulson, Paul Nghiem… in Scientific Reports (2016)

    Download PDF (5864 KB) View Article