7 Result(s)
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Article
Dao Qing Dai
Algorithms
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Article
Open AccessDetecting overlap** protein complexes based on a generative model with functional and topological properties
Identification of protein complexes can help us get a better understanding of cellular mechanism. With the increasing availability of large-scale protein-protein interaction (PPI) data, numerous computational ...
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Article
Open AccessDetecting temporal protein complexes from dynamic protein-protein interaction networks
Proteins dynamically interact with each other to perform their biological functions. The dynamic operations of protein interaction networks (PPI) are also reflected in the dynamic formations of protein complex...
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Open AccessDetermining minimum set of driver nodes in protein-protein interaction networks
Recently, several studies have drawn attention to the determination of a minimum set of driver proteins that are important for the control of the underlying protein-protein interaction (PPI) networks. In gener...
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Open AccessA two-layer integration framework for protein complex detection
Protein complexes carry out nearly all signaling and functional processes within cells. The study of protein complexes is an effective strategy to analyze cellular functions and biological processes. With the ...
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Open AccessRegularized logistic regression with network-based pairwise interaction for biomarker identification in breast cancer
To facilitate advances in personalized medicine, it is important to detect predictive, stable and interpretable biomarkers related with different clinical characteristics. These clinical characteristics may be...
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Open AccessComparative analysis of housekee** and tissue-specific driver nodes in human protein interaction networks
Several recent studies have used the Minimum Dominating Set (MDS) model to identify driver nodes, which provide the control of the underlying networks, in protein interaction networks. There may exist multiple...
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Article
Open AccessProtein complex detection based on partially shared multi-view clustering
Protein complexes are the key molecular entities to perform many essential biological functions. In recent years, high-throughput experimental techniques have generated a large amount of protein interaction da...
