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  1. No Access

    Article

    Prevention of graft-versus-host disease (GVHD) by elimination of recipient-reactive donor T cells with recombinant toxins that target the interleukin 2 (IL-2) receptor

    Graft-versus-host disease (GVHD), due to the presence of recipient-reactive T cells, limits the usefulness of bone marrow transplantation (BMT) and is a major contributor to patient mortality. To prevent GVHD,...

    DT Harris, D Sakiestewa, C Lyons, RJ Kreitman, I Pastan in Bone Marrow Transplantation (1999)

  2. No Access

    Article

    Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7

    We have completed a phase I study to test feasibility and toxicity of immunotherapy of hepatic metastases from colorectal carcinoma by direct gene transfer of HLA-B7, a MHC class I gene. Eligible patients were...

    J Rubin, E Galanis, HC Pitot, RL Richardson, PA Burch, JW Charboneau… in Gene Therapy (1997)