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Article
Myelination by transplanted human and mouse central nervous system tissue after long-term cryopreservation
Human and mouse oligodendrocytes were transplanted, after a long period of cryostorage, into newborn mouse brain. Tissue fragments were obtained from brain and spinal cord of 10-week-old human fetuses and fro...
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Article
Tumor necrosis factor-α, microglia and astrocytes in AIDS dementia complex
The pathogenesis of HIV-associated cognitive changes is poorly understood. Cytokines such as tumor necrosis factor-α (TNF-α) have been postulated to contribute to the mechanism of the neurological complicatio...
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Article
The relationship between Bunina bodies, skein-like inclusions and neuronal loss in amyotrophic lateral sclerosis
Specific pathological hallmarks have been described in amyotrophic lateral sclerosis (ALS), which include motor neuronal loss, Bunina bodies (BBs) and skein like inclusions (SLIs). We investigated the relatio...
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Article
How a neuropsychiatric brain bank should be run: a consensus paper of Brainnet Europe II
The development of new molecular and neurobiological methods, computer-assisted quantification techniques and neurobiological investigation methods which can be applied to the human brain, all have evoked an i...
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Article
Wernicke encephalopathy and Creutzfeldt-Jakob disease
We assessed the prevalence of Wernicke encephalopathy (WE) in all 657 cases suspected of Creutzfeldt-Jakob (CJD) referred from 2001 to 2006 to the French Neuropathology Network of CJD. Clinical, biological and...
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Article
IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease that primarily affects motoneurons in the brain and spinal cord. Dominant mutations in superoxide dismutase-1 (SOD1) cause a famili...
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Article
Quelle place pour l’autopsie médicale en 2015 ?
