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Impact of EASO/ESPEN-Defined Sarcopenic Obesity Following a Technology-Based Weight Loss Intervention

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  1. Article

    Open Access

    Association between cervical artery dissection and spinal manipulative therapy –a medicare claims analysis

    Cervical artery dissection and subsequent ischemic stroke is the most serious safety concern associated with cervical spinal manipulation.

    James M Whedon, Curtis L Petersen, Zhongze Li, William J Schoelkopf in BMC Geriatrics (2022)

  2. Article

    Open Access

    DNA 5-hydroxymethylcytosine in pediatric central nervous system tumors may impact tumor classification and is a positive prognostic marker

    Nucleotide-specific 5-hydroxymethylcytosine (5hmC) remains understudied in pediatric central nervous system (CNS) tumors. 5hmC is abundant in the brain, and alterations to 5hmC in adult CNS tumors have been re...

    Nasim Azizgolshani, Curtis L. Petersen, Youdinghuan Chen in Clinical Epigenetics (2021)

  3. Article

    Open Access

    MethylSPWNet and MethylCapsNet: Biologically Motivated Organization of DNAm Neural Networks, Inspired by Capsule Networks

    DNA methylation (DNAm) alterations have been heavily implicated in carcinogenesis and the pathophysiology of diseases through upstream regulation of gene expression. DNAm deep-learning approaches are able to c...

    Joshua J. Levy, Youdinghuan Chen in npj Systems Biology and Applications (2021)

  4. Article

    Open Access

    Weight management intervention identifies association of decreased DNA methylation age with improved functional age measures in older adults with obesity

    Assessing functional ability is an important component of understanding healthy aging. Objective measures of functional ability include grip strength, gait speed, sit-to-stand time, and 6-min walk distance. Us...

    Curtis L. Petersen, Brock C. Christensen, John A. Batsis in Clinical Epigenetics (2021)

  5. Article

    Open Access

    Feasibility and acceptability of a technology-based, rural weight management intervention in older adults with obesity

    Older adults with obesity residing in rural areas have reduced access to weight management programs. We determined the feasibility, acceptability and preliminary outcomes of an integrated technology-based heal...

    John A. Batsis, Curtis L. Petersen, Matthew M. Clark, Summer B. Cook in BMC Geriatrics (2021)

  6. Article

    Open Access

    Altered immune phenotype and DNA methylation in panic disorder

    Multiple studies have related psychiatric disorders and immune alterations. Panic disorder (PD) has been linked with changes in leukocytes distributions in several small studies using different methods for imm...

    Curtis L. Petersen, Ji-Qing Chen, Lucas A. Salas in Clinical Epigenetics (2020)

  7. Article

    Open Access

    MethylNet: an automated and modular deep learning approach for DNA methylation analysis

    DNA methylation (DNAm) is an epigenetic regulator of gene expression programs that can be altered by environmental exposures, aging, and in pathogenesis. Traditional analyses that associate DNAm alterations wi...

    Joshua J. Levy, Alexander J. Titus, Curtis L. Petersen in BMC Bioinformatics (2020)