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  1. Article

    Open Access

    MethylSPWNet and MethylCapsNet: Biologically Motivated Organization of DNAm Neural Networks, Inspired by Capsule Networks

    DNA methylation (DNAm) alterations have been heavily implicated in carcinogenesis and the pathophysiology of diseases through upstream regulation of gene expression. DNAm deep-learning approaches are able to c...

    Joshua J. Levy, Youdinghuan Chen… in npj Systems Biology and Applications (2021)

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  2. Article

    Open Access

    MethylNet: an automated and modular deep learning approach for DNA methylation analysis

    DNA methylation (DNAm) is an epigenetic regulator of gene expression programs that can be altered by environmental exposures, aging, and in pathogenesis. Traditional analyses that associate DNAm alterations wi...

    Joshua J. Levy, Alexander J. Titus, Curtis L. Petersen… in BMC Bioinformatics (2020)

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