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    Article

    Tyrosine Kinase Inhibitor Si409 Has In Vitro and In Vivo Anti-Tumor Activity Against Diffuse Large B-Cell Lymphoma

    The abnormal activation of Src family kinases (SFKs) due to deregulation of the B-cell receptor (BCR) signalling pathway provides a promising target for development of new pharmacological strategy to overcome ...

    Enrico Rango, Salvatore Di Maria, Claudio Zamperini in Pharmaceutical Chemistry Journal (2023)

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    Open Access

    Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery

    Pyrazolo[3,4-d]pyrimidines are a class of compounds with a good activity against several cancer cell lines. Despite the promising anticancer activity, these molecules showed a poor aqueous solubility. This issue ...

    Giulia Vignaroli, Pierpaolo Calandro, Claudio Zamperini in Scientific Reports (2016)