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  1. Article

    Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-Like Behavior in Hypoglutamatergic Mice

    Current antipsychotic drugs (APDs) show efficacy with positive symptoms, but are limited in treating negative or cognitive features of schizophrenia. Whereas all currently FDA-approved medications target prima...

    Su M Park, Meng Chen, Claire M Schmerberg, Russell S Dulman… in Neuropsychopharmacology (2016)

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  2. Article

    5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice

    All FDA-approved antipsychotic drugs (APDs) target primarily dopamine D2 or serotonin (5-HT2A) receptors, or both; however, these medications are not universally effective, they may produce undesirable side effec...

    Vladimir M Pogorelov, Ramona M Rodriguiz, Jianjun Cheng… in Neuropsychopharmacology (2017)

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