100 Result(s)
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Article
Use of PEI-coated magnetic iron oxide nanoparticles as gene vectors
To evaluate the feasibility of using polyethyleneimine (PEI) coated magnetic iron oxide nanoparticles (polyMAG-1000) as gene vectors. The surface characteristics of the nanoparticles were observed with scannin...
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Article
Identification of colorectal cancer using proteomic patterns in serum
At present there are no serological indicators with high sensitivity and specificity to diagnose colorectal cancer (CRC). This study was designed to establish a serum protein fingerprinting technique coupled w...
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Article
Relationship between carbachol hyperstimulation-induced pancreatic acinar cellular injury and trypsinogen or NF-κB activation in ratsin vitro
The relationship between M3 cholinergic receptor agonist (carbachol) hyperstimulation-induced pancreatic acinar cellular injury and trypsinogen activation or NF-κB activation in rats was studiedin vitro. Rat panc...
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Article
Construction and expression of human PTEN tumor suppressor gene recombinant adenovirus vector
The recombinant defective adenovirus vector carrying human PTEN tumor suppressor gene was constructed by using AdEasy-1 system and its expression was detected in human breast cancer cell line MDA-MB-468. Human...
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Article
Erythrocyte omega-3 and omega-6 polyunsaturated fatty acids and preeclampsia risk in Peruvian women
Objective: This case–control study was conducted in Lima, Peru, from June 1997 through January 1998 to assess whether alteration in maternal erythrocyte omega-3 (n-3) and omega-6 (n-6) fa...
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Article
Inhibition of RAW264.7 macrophage inflammatory cytokines release by small haparin RNAi targeting TLR4
In order to construct an expression vector carrying small hairpin (sh) RNA (shRNA) for toll-like receptor 4 mRNA and a reporter gene of enhanced green fluorescence protein (EGFP) and study the inhibition of cy...
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Article
Magnetic iron oxide nanoparticles mediated gene therapy for breast cancer — An In Vitro study
The aim of this study was to evaluate the feasibility and efficacy of using TRAIL gene to treat breast cancer mediated with a novel carrier — magnetic iron oxide nanoparticles (polyMAG-1000) coated with PEI. T...
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Article
Exogenous PTEN gene induces apoptosis in breast carcinoma cell line MDA468
The effects and mechanisms of exogenous phosphatase and tensin homolog deleted from chromosome ten (PTEN) gene on phosphatase activity-dependent apoptosis of breast cancer cell line MDA468 were investigated. P...
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Open AccessAssociations of depression and depressive symptoms with preeclampsia: results from a Peruvian case-control study
Preeclampsia involves endothelial dysfunction, platelet dysfunction/activation and sympathetic over-activity similar to cardiovascular disorders (CVD). Depression, an independent risk factor for progression of...
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Article
Expressions of cyclooxygenase-2 and matrix metalloproteinase-9 in cervical carcinoma and their clinical significance
To investigate the expressions of cyclooxygenase (COX)-2 and matrix metalloproteinase (MMP)-9 in cervical carcinoma and their clinical significance.
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Article
Relationship between carbachol hyperstimulation-induced pancreatic intracelluar trypsinogen and NF-κB activation in rats in vitro
The relationship between intracelluar trypsinogen activation and NF-κB activation in rat pancreatic acinar cells induced by M3 cholinergic receptor agonist (carbachol) hyperstimulation was studied. Rat pancrea...
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Article
Relationship between prognosis and angiogenesis, lymphangiogenesis, proliferative cell distribution in gastric cancer
We investigated the relationship between lymphangiogenesis, angiogenesis and cell proliferation in gastric cancer.
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Article
Open AccessEarly pregnancy peripheral blood gene expression and risk of preterm delivery: a nested case control study
Preterm delivery (PTD) is a significant public health problem associated with greater risk of mortality and morbidity in infants and mothers. Pathophysiologic processes that may lead to PTD start early in preg...
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Article
A prospective randomized placebo-controlled study of the effect of acupuncture in infertile patients with severe oligoasthenozoospermia
In this first prospective, randomized, single-blind, placebo-controlled study, 28 infertile patients with severe oligoasthenozoospermia received acupuncture according to the principles of traditional Chinese m...
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Article
Open AccessGlucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot study
Insufficient sleep and poor sleep quality, considered endemic in modern society, are associated with obesity, impaired glucose tolerance and diabetes. Little, however, is known about the consequences of insuff...
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Reversal of P-glycoprotein-mediated multidrug resistance in SGC7901/VCR cells by PPARγ activation by troglitazone
Over-expression of P-glycoprotein (P-gp), an ATP-dependent drug efflux pump, represents one of the major mechanisms that contribute to multidrug resistance (MDR) in cancer cells. This study examined the effect...
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Article
Open AccessSleep duration, vital exhaustion and perceived stress among pregnant migraineurs and non-migraineurs
Migraine has been associated with sleep disorders in men and non-pregnant women, but little is known about sleep complaints among pregnant migraineurs.
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Article
AMP-Activated Protein Kinase Inhibits Homocysteine-Induced Dysfunction and Apoptosis in Endothelial Progenitor Cells
Homocysteine (Hcy) has been shown to induce oxidative stress and apoptosis of endothelial progenitor cells (EPCs). AMP-activated protein kinase (AMPK) has been reported to have protective effects on endothelia...
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Article
Open AccessAssociation between metabolic abnormalities and HBV related hepatocelluar carcinoma in Chinese: A cross-sectional study
Previous studies suggested that the abnormality of metabolism is a newly identified risk factor in HBV-related hepatocellular carcinoma (HCC). The association between metabolic factors and hepatocellular carci...
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Article
Open AccessMultifocal Langerhans cell sarcoma involving epidermis: a case report and review
To study the clinico-pathological characteristics of Langerhans cell sarcoma (LCS) which involving epidermis.
