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  1. No Access

    Article

    Differential DNA Methylation Status Between Human Preadipocytes and Mature Adipocytes

    Obesity is a multifactorial disease resulting from interactions between susceptibility genes, psychosocial, and environmental factors. However, it is becoming evident that interindividual differences in obesit...

    **-gai Zhu, Li **a, Chen-bo Ji, Chun-mei Zhang… in Cell Biochemistry and Biophysics (2012)

  2. No Access

    Article

    Overexpression of TFAM Protects 3T3-L1 Adipocytes from NYGGF4 (PID1) Overexpression-Induced Insulin Resistance and Mitochondrial Dysfunction

    NYGGF4, also known as phosphotyrosine interaction domain containing 1(PID1), is a recently discovered gene which is involved in obesity-related insulin resistance (IR) and mitochondrial dysfuncti...

    Chun-Mei Shi, Guang-Feng Xu, Lei Yang, Zi-Yi Fu… in Cell Biochemistry and Biophysics (2013)

  3. No Access

    Article

    Characterization of microRNA expression profiles in 3T3-L1 adipocytes overexpressing C10orf116

    Our data in the previous report demonstrated that C10orf116 (AFRO) is an adipocyte lineage-specific nuclear factor that can modulate the master adipogenesis transcription factors early during differentiation. ...

    Jie Qiu, **ao-guang Zhou, **ao-yu Zhou, Chun Zhu, Chun-mei Shi… in Molecular Biology Reports (2013)

  4. No Access

    Article

    MiR-335, an Adipogenesis-Related MicroRNA, is Involved in Adipose Tissue Inflammation

    During the development of obesity, adipose tissue releases a host of different adipokines and inflammatory cytokines, such as leptin, resistin, tumor necrosis factor α (TNF-α), Interleukin-6 (IL-6), and adipon...

    Lu Zhu, Ling Chen, Chun-Mei Shi, Guang-Feng Xu… in Cell Biochemistry and Biophysics (2014)

  5. No Access

    Article

    Knockdown of LYRM1 Rescues Insulin Resistance and Mitochondrial Dysfunction Induced by FCCP in 3T3-L1 Adipocytes

    LYR motif-containing 1 (LYRM1) was recently discovered to be involved in adipose tissue homeostasis and obesity-associated insulin resistance. We previously demonstrated that LYRM1 overexpression might contribute...

    Min Zhang, Zhen-Ying Qin, Yong-mei Dai, Yu-Mei Wang… in Cell Biochemistry and Biophysics (2014)

  6. No Access

    Article

    TNF-α, IL-6, and Leptin Increase the Expression of miR-378, an Adipogenesis-Related microRNA in Human Adipocytes

    Obesity has become a global public health problem associated with complications including type 2 diabetes, cardiovascular disease, and several cancers. Adipocyte differentiation (adipogenesis) plays an importa...

    Lu-lian Xu, Chun-mei Shi, Guang-feng Xu, Ling Chen… in Cell Biochemistry and Biophysics (2014)

  7. Article

    The biological effects of hsa-miR-1908 in human adipocytes

    MicroRNAs (miRNAs) are small non-coding RNAs involved in the regulation of gene expression. MiR-1908 is a recently identified miRNA that is highly expressed in human adipocytes. However, it is not known what r...

    Lei Yang, Chun-mei Shi, Ling Chen, Ling-xia Pang… in Molecular Biology Reports (2015)

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    Article

    Transcriptome analysis reveals the potential contribution of long noncoding RNAs to brown adipocyte differentiation

    Brown adipose tissue (BAT) functions to dissipate energy in response to cold exposure or overfeeding. Counteracting obesity has been extensively considered as a promising target. Long noncoding RNAs (lncRNAs) ...

    Liang hui You, Li jun Zhu, Lei Yang, Chun mei Shi… in Molecular Genetics and Genomics (2015)