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Article
Circulating levels of adiponectin, resistin, and visfatin after mud-bath therapy in patients with bilateral knee osteoarthritis
Adipocytokines, including adiponectin, resistin, and visfatin may play an important role in the pathophysiology of osteoarthritis (OA). Spa therapy is one of the most commonly used non-pharmacological approach...
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Article
Clinical and biochemical effects of a 3-week program of diet combined with spa therapy in obese and diabetic patients: a pilot open study
Obesity is a major risk factor for arterial hypertension, coronary artery disease, dyslipidemias, and type 2 diabetes. Spa therapy has long been used for treating obesity and its comorbidities. Enlargement of ...
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Article
Short- and long-term effects of mud-bath treatment on hand osteoarthritis: a randomized clinical trial
The aim of this study was to evaluate both the short-term and the long-term effectiveness of spa therapy in patients with primary hand osteoarthritis (OA). This was a prospective randomized, single blind contr...
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Article
Efficacy of balneotherapy on pain, function and quality of life in patients with osteoarthritis of the knee
The aims of this study were to evaluate whether balneotherapy with mineral sulphate–bicarbonate–calcium water could determine substantial symptomatic improvement, and to detect any changes in the quality of li...