24 Result(s)

Article

Isoquinoline-catalyzed addition of 2-bromo-1-aryl-1-ethanone to dialkyl azodicarboxylate: synthesis of trialkyl 2-[(1E)-N-(alkoxycarbonyl)-2-aryl-2-oxoethanehydrazonoyl]hydrazine-1,1,2-tricarboxylate

A catalytic method for the synthesis of a class of hydrazine derivatives is reported. The described method provides convenient access to compounds which are anticipated to show biological activities. The salie...

Ebrahim Kianmehr, Alireza Bakhtiary… in Monatshefte für Chemie - Chemical Monthly (2012)

Article

Selenium nanoparticles decorated with Ulva lactuca polysaccharide potentially attenuate colitis by inhibiting NF-κB mediated hyper inflammation

Selenium (Se) is an essential micronutrient trace element and an established nutritional antioxidant. Low Se status exacerbates inflammatory bowel diseases progression, which involves hyper inflammation in the...

Chenghui Zhu, Shuimei Zhang, Chengwei Song, Yibo Zhang… in Journal of Nanobiotechnology (2017)

Article

A novel strategy to improve protein secretion via overexpression of the SppA signal peptide peptidase in Bacillus licheniformis

Signal peptide peptidases play an important role in the removal of remnant signal peptides in the cell membrane, a critical step for extracellular protein production. Although these proteins are likely a centr...

Dongbo Cai, Hao Wang, Penghui He, Chengjun Zhu, Qin Wang… in Microbial Cell Factories (2017)

Article

Plastic bag as horizontal photobioreactor on rocking platform driven by water power for culture of alkalihalophilic cyanobacterium

Mixing in traditional algae culture system consumes intensive electricity. This should be replaced by nature force to reduce energy cost and, more importantly, to realize positive energy balance of algal biofu...

He Zhu, Chenba Zhu, Longyan Cheng, Zhanyou Chi in Bioresources and Bioprocessing (2017)

Article

A recycling culture of Neochloris oleoabundans in a bicarbonate-based integrated carbon capture and algae production system with harvesting by auto-flocculation

A bicarbonate-based integrated carbon capture and algae production system (BICCAPS) uses carbonate to capture CO₂ and produce bicarbonate for alkalihalophilic microalgal cultivation. In this process, carbonate is...

Chenba Zhu, Ruolan Zhang, Longyan Cheng, Zhanyou Chi in Biotechnology for Biofuels (2018)

Article

Hydrodynamic performance of floating photobioreactors driven by wave energy

Unlike conventional cultivation systems, liquid mixing in floating photobioreactors (PBRs) is solely induced by their hydrodynamic movement in response to waves, and this movement is affected by the wave condi...

Chenba Zhu, Zhanyou Chi, Chunwei Bi, Yunpeng Zhao, Haibo Cai in Biotechnology for Biofuels (2019)

Article

Rapid generation and selection of Cas9-engineering TRP53 R172P mice that do not have off-target effects

Genetic mutations cause severe human diseases, and suitable animal models to study the regulatory mechanisms involved are required. The CRISPR/Cas9 system is a powerful, highly efficient and easily manipulated...

Guoxing Zheng, Qingqing Zhu, Junchao Dong, **n Lin, Chengming Zhu in BMC Biotechnology (2019)

Article

ImmunoPET imaging of human CD8⁺ T cells with novel ⁶⁸Ga-labeled nanobody companion diagnostic agents

Although immunotherapy has revolutionized treatment strategies for some types of cancers, most patients failed to respond or obtain long-term benefit. Tumor-infiltrating CD8⁺ T lymphocytes are closely related to ...

Haitao Zhao, Chao Wang, Yanling Yang, Yan Sun, Weijun Wei… in Journal of Nanobiotechnology (2021)

Article

Author Correction: Molecular engineering of organic–inorganic hybrid perovskites quantum wells

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Yao Gao, Enzheng Shi, Shibin Deng, Stephen B. Shiring… in Nature Chemistry (2021)

Article

Expression of a recombinant FLT3 ligand and its emtansine conjugate as a therapeutic candidate against acute myeloid leukemia cells with FLT3 expression

Most patients with acute myeloid leukemia (AML) remain uncurable and require novel therapeutic methods. Gain-of-function FMS-like tyrosine kinase 3 (FLT3) mutations are present in 30–40% of AML patients and se...

Dengyang Zhang, Yao Guo, Yuming Zhao, Liuting Yu… in Microbial Cell Factories (2021)

Article

Redirection of the central metabolism of Klebsiella pneumoniae towards dihydroxyacetone production

Klebsiella pneumoniae is a bacterium that can be used as producer for numerous chemicals. Glycerol can be catabolised by K. pneumoniae and dihydroxyacetone is an intermediate of this catabolism pathway. Here dihy...

Shaoqi Sun, Yike Wang, Lin Shu, **yang Lu, Qinghui Wang… in Microbial Cell Factories (2021)

Article

Biosynthesis of lactones from diols mediated by an artificial flavin

Lactones are important compounds in the field of medicine, material and chemical industry. One of the promising accesses to these flexible scaffolds is NAD(P)⁺-dependent alcohol dehydrogenases-catalyzed oxidative...

**aowang Zhang, Zhuotao Tan, Chaojian Li, Siyu Qi… in Bioresources and Bioprocessing (2021)

Article

MXene-assisted organic electrochemical transistor biosensor with multiple spiral interdigitated electrodes for sensitive quantification of fPSA/tPSA

The ratio of fPSA/tPSA in the "grey zone" of tPSA with the concentration range between 4 ng/ml and 10 ng/ml is significant for diagnosis of prostate cancer, and highly efficiency quantification of the ratio of...

Yi-Cheng Zhu, Biao Cai, Quan Jiang, Yuan Zhang, Jianjun Sha… in Journal of Nanobiotechnology (2021)

Article

Acupoint nanocomposite hydrogel for simulation of acupuncture and targeted delivery of triptolide against rheumatoid arthritis

Attenuating inflammatory response and relieving pain are two therapeutic therapeutical goals for rheumatoid arthritis (RA). Anti-inflammatory and analgesic drugs are often associated with many adverse effects ...

Shu**g Ren, Heng Liu, **tong Wang, Jiquan Bi, Shengfeng Lu… in Journal of Nanobiotechnology (2021)

Article

Carrier-free multifunctional nanomedicine for intraperitoneal disseminated ovarian cancer therapy

Ovarian cancer is the most lethal gynecological cancer which is characterized by extensive peritoneal implantation metastasis and malignant ascites. Despite advances in diagnosis and treatment in recent years,...

**uyu Huang, Miaojuan Qiu, Tianqi Wang, Binbin Li… in Journal of Nanobiotechnology (2022)

Article

Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer

The development of multidrug resistance (MDR) during cancer chemotherapy is a major challenge in current cancer treatment strategies. Numerous molecular mechanisms, including increased drug efflux, evasion of ...

**angyang Zhang, Min Wang, Junyi Feng, Bin Qin… in Journal of Nanobiotechnology (2022)

Article

An injectable photo-cross-linking silk hydrogel system augments diabetic wound healing in orthopaedic surgery through spatiotemporal immunomodulation

The complicated hyperglycaemic and chronic inflammation of diabetic wounds in orthopaedic surgery leads to dysregulated immune cell function and potential infection risk. Immune interventions in diabetic wound...

Jiawei Mei, Jun Zhou, Lingtong Kong, Yong Dai… in Journal of Nanobiotechnology (2022)

Article

Enhanced accumulation of oil through co-expression of fatty acid and ABC transporters in Chlamydomonas under standard growth conditions

Chloroplast and endoplasmic reticulum (ER)-localized fatty acid (FA) transporters have been reported to play important roles in oil (mainly triacylglycerols, TAG) biosynthesis. However, whether these FA transp...

Ru Chen, Miao Yang, Mengjie Li, Hao Zhang… in Biotechnology for Biofuels and Bioproducts (2022)

Article

Local delivery of gaseous signaling molecules for orthopedic disease therapy

Over the past decade, a proliferation of research has used nanoparticles to deliver gaseous signaling molecules for medical purposes. The discovery and revelation of the role of gaseous signaling molecules hav...

Jiaxuan Sun, Wenzhi Wang, **anli Hu, **anzuo Zhang… in Journal of Nanobiotechnology (2023)

Article

Advanced biomass materials: progress in the applications for energy, environmental, and emerging fields

Shuangxi Nie, Chaoji Chen, Chenjie Zhu in Frontiers of Chemical Science and Engineering (2023)