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  1. Article

    Short-term postoperative outcomes for obese versus non-obese inflammatory bowel disease patients undergoing bowel resection: a propensity score matched analysis

    Up to 40% of patients with inflammatory bowel disease (IBD) are obese. Obesity is a well-known risk factor for increased perioperative morbidity, but this risk has never been quantified in IBD patients undergo...

    Lily Park, Tyler McKechnie, Yung Lee in International Journal of Colorectal Disease (2024)

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    Primary anastomosis with diverting loop ileostomy versus Hartmann’s procedure for acute complicated diverticulitis: analysis of the National Inpatient Sample 2015–2019

    Up to 50% of patients with acute complicated diverticulitis require operative management on their index admission. There is ongoing debate as to whether primary anastomosis with diverting ileostomy versus a Ha...

    Yung Lee, Tyler McKechnie in International Journal of Colorectal Disease (2023)

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    Article

    HEmoRhoidal disease management with Band ligation versus polidocanol Sclerotherapy: a systematic review and meta-analysis (the HerBS Review)

    Symptomatic internal hemorrhoids affect up to 40% of people in Western society. Patients with grade I–III hemorrhoids, who fail lifestyle and medical management, may benefit from office-based procedures. As pe...

    Janhavi Patel, Tyler McKechnie, Kathy Wu in International Journal of Colorectal Disease (2023)

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    Perioperative intravenous dexamethasone for patients undergoing colorectal surgery: a systematic review and meta-analysis

    Dexamethasone is a glucocorticoid that is often administered intraoperatively as prophylaxis for postoperative nausea and vomiting (PONV). Several randomized controlled trials (RCTs) have examined its use in c...

    Tyler McKechnie, Geoffrey Elder in International Journal of Colorectal Disease (2023)

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    Preoperative carbohydrate loading before colorectal surgery: a systematic review and meta-analysis of randomized controlled trials

    Preoperative carbohydrate loading has been introduced as a component of many enhanced recovery after surgery programs. Evaluation of current evidence for preoperative carbohydrate loading in colorectal surgery...

    Justin Lu, Jigish Khamar, Tyler McKechnie in International Journal of Colorectal Disease (2022)

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    Article

    Short-stay compared to long-stay admissions for loop ileostomy reversals: a systematic review and meta-analysis

    Short-stay admissions, with lengths of stay less than 24 h, are used for various surgeries without increasing adverse events. However, it is unclear if short-stay admissions would be safe for loop ileostomy re...

    Victoria Archer, Zacharie Cloutier in International Journal of Colorectal Disease (2022)

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    Concurrent use of statins and neoadjuvant chemoradiotherapy for rectal cancer: a systematic review and meta-analysis

    Statins are used primarily in patients with cardiovascular disease. More recently, they have demonstrated benefit in oncology patients. In vitro models have shown decreased rectal tumor cell viability in cells...

    Tyler McKechnie, Gaurav Talwar, Yung Lee in International Journal of Colorectal Disease (2021)

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    Radiotherapy alone versus chemoradiotherapy for stage I anal squamous cell carcinoma: a systematic review and meta-analysis

    Patients with stage I anal squamous cell carcinoma (SCC) have been underrepresented in landmark trials showing superiority of chemoradiotherapy over radiotherapy for definitive treatment. This review aims to e...

    Gaurav Talwar, Ryan Daniel, Tyler McKechnie in International Journal of Colorectal Disease (2021)

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    The role of fecal calprotectin in the diagnosis of acute pouchitis following IPAA for ulcerative colitis: a systematic clinical review

    Total proctocolectomy (TPC) with ileal pouch anal anastomosis (IPAA) is commonly performed for patients with refractory ulcerative colitis (UC). Pouchitis occurs in 20–50% of these patients. Fecal calprotectin...

    Tyler McKechnie, Yung Lee, Colin Kruse in International Journal of Colorectal Disease (2020)

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    Diverting loop ileostomy with colonic lavage as an alternative to colectomy for fulminant Clostridioides difficile: a systematic review and meta-analysis

    Surgical consultation is recommended for all patients with fulminant Clostridioides difficile infection (CDI). If surgery is required, total abdominal colectomy (TAC) is most commonly performed. However, divertin...

    Tyler McKechnie, Yung Lee in International Journal of Colorectal Disease (2020)

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    Article

    Optimal timing of urinary catheter removal following pelvic colorectal surgery: a systematic review and meta-analysis

    Acute urinary retention (AUR) is a common postoperative complication in colorectal surgery. In pelvic colorectal operations, the optimal duration for postoperative urinary catheter use is controversial. This s...

    Yung Lee, Tyler McKechnie in International Journal of Colorectal Disease (2019)