21 Result(s)

Article

Health-related quality of life (HRQoL) after different axillary treatments in women with breast cancer: a 1-year longitudinal cohort study

As life expectancy continues to rise, post-treatment health-related quality of life (HRQoL) of breast cancer patients becomes increasingly important. This study examined the one-year longitudinal relation betw...

N. J. M. C. Vrancken Peeters, Z. L. R. Kaplan, M. E. Clarijs… in Quality of Life Research (2024)

Article

Can we use a simple blood test to reduce unnecessary adverse effects from radiotherapy by timely identification of radiotherapy-resistant rectal cancers? MeD-Seq rectal study protocol

Chemoradiation therapy (CRT) followed by surgery is currently the standard of care to treat patients with locally advanced rectal cancer (LARC). CRT reduces local recurrences, but is associated with significan...

D. M. Mens, J. M. van Rees, S. M. Wilting, C. Verhoef in BMC Cancer (2023)

Article

Markers for Major Complications at Day-One Postoperative in Fast-Track Metabolic Surgery: Updated Metabolic Checklist

In fast-track metabolic surgery, the window to identify complications is narrow. Postoperative checklists can be useful tools in the decision-making of safe early discharge. The aim of this study was to evalua...

J. W. H. ‘t Hart, R. Takken, C. R. C. Hogewoning, L. U. Biter… in Obesity Surgery (2023)

Article

Histopathological growth patterns of neuroendocrine tumor liver metastases

Histopathological growth patterns (HGPs) of liver metastases represent a potential biomarker for prognosis after resection. They have never been studied in neuroendocrine tumor liver metastases (NETLM). This s...

Y. Meyer, A. Bohlok, P. Olthof, V. Donckier… in Clinical & Experimental Metastasis (2023)

Article

Circulating tumour cells are associated with histopathological growth patterns of colorectal cancer liver metastases

Histopathological Growth Patterns (HGPs) have prognostic and predictive value in patients with Colorectal Liver Metastases (CRLM). This study examined whether preoperative measurement of Circulating Tumour Cel...

Y. M. Meyer, S. M. Wilting, J. Kraan, P. Olthof… in Clinical & Experimental Metastasis (2023)

Article

Implementation of robotic rectal cancer surgery: a cross-sectional nationwide study

An increasing number of centers have implemented a robotic surgical program for rectal cancer. Several randomized controls trials have shown similar oncological and postoperative outcomes compared to standard ...

L. J. X. Giesen, J. W. T. Dekker, M. Verseveld, R. M. P. H. Crolla… in Surgical Endoscopy (2023)

Article

Neoadjuvant FOLFOXIRI prior to chemoradiotherapy for high-risk (“ugly”) locally advanced rectal cancer: study protocol of a single-arm, multicentre, open-label, phase II trial (MEND-IT)

The presence of mesorectal fascia (MRF) invasion, grade 4 extramural venous invasion (EMVI), tumour deposits (TD) or extensive or bilateral extramesorectal (lateral) lymph nodes (LLN) on MRI has been suggested...

K. van den Berg, D. P. Schaap, E. L. K. Voogt, T. E. Buffart… in BMC Cancer (2022)

Article

Treatment Strategies and Prognosis of Patients With Synchronous or Metachronous Colorectal Peritoneal Metastases: A Population-Based Study

This study aimed to compare treatment strategies and survival of patients with synchronous colorectal peritoneal metastases (CPM) and patients with metachronous CPM in a nationwide cohort.

C. Bakkers, R. J. Lurvink, A. Rijken, S. W. Nienhuijs… in Annals of Surgical Oncology (2021)

Article

Clinical added value of MRI to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO): study protocol for an international multicentre prospective diagnostic accuracy study

Abdominal computed tomography (CT) is the standard imaging method for patients with suspected colorectal liver metastases (CRLM) in the diagnostic workup for surgery or thermal ablation. Diffusion-weighted and...

B. Görgec, I. Hansen, G. Kemmerich, T. Syversveen, M. Abu Hilal… in BMC Cancer (2021)

Article

Relation between body composition and severe diarrhea in patients treated with preoperative chemoradiation with capecitabine for rectal cancer: a single-centre cohort study

Chemoradiation with capecitabine followed by surgery is standard care for locally advanced rectal cancer (LARC). Severe diarrhea is considered a dose-limiting toxicity of adding capecitabine to radiation thera...

J. M. van Rees, W. Hartman, J. J. M. E. Nuyttens, E. Oomen-de Hoop… in BMC Gastroenterology (2021)

Article

Patient-Reported Outcome Measures may optimize shared decision-making for cancer risk management in BRCA mutation carriers

The aim of this study was to compare patient-reported outcomes (PROs) of BRCA1/2 mutation carriers, either after bilateral prophylactic mastectomy (BPM) or during breast surveillance, to improve shared decisio...

L. S. E. van Egdom, M. A. de Kock, I. Apon, M. A. M. Mureau, C. Verhoef… in Breast Cancer (2020)

Article

Histopathological growth patterns of colorectal liver metastasis exhibit little heterogeneity and can be determined with a high diagnostic accuracy

Colorectal liver metastases (CRLM) exhibit distinct histopathological growth patterns (HGPs) that are indicative of prognosis following surgical treatment. This study aims to assess the reliability and replica...

D. J. Höppener, P. M. H. Nierop, E. Herpel… in Clinical & Experimental Metastasis (2019)

Article

Adjuvant hepatic arterial infusion pump chemotherapy and resection versus resection alone in patients with low-risk resectable colorectal liver metastases – the multicenter randomized controlled PUMP trial

Recurrences are reported in 70% of all patients after resection of colorectal liver metastases (CRLM), in which half are confined to the liver. Adjuvant hepatic arterial infusion pump (HAIP) chemotherapy aims ...

F. E. Buisman, M. Y. V. Homs, D. J. Grünhagen, W. F. Filipe, R. J. Bennink… in BMC Cancer (2019)

Article

Breast and Tumour Volume Measurements in Breast Cancer Patients Using 3-D Automated Breast Volume Scanner Images

The resection volume in relation to the breast volume is known to influence cosmetic outcome following breast-conserving therapy. It was hypothesised that three-dimensional ultrasonography (3-D US) could be us...

M. Lagendijk, E. L. Vos, K. P. Ramlakhan, C. Verhoef… in World Journal of Surgery (2018)

Article

TUmor-volume to breast-volume RAtio for improving COSmetic results in breast cancer patients (TURACOS); a randomized controlled trial

Cosmetic result following breast conserving surgery (BCS) for cancer influences quality of life and psychosocial functioning in breast cancer patients. A preoperative prediction of expected cosmetic result fol...

M. Lagendijk, E. L. Vos, A. H. J. Koning, M. G. M. Hunink, J. P. Pignol… in BMC Cancer (2017)

Article

MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing

MicroRNAs (miRs) have been recognized as promising biomarkers. It is unknown to what extent tumor-derived miRs are differentially expressed between primary colorectal cancers (pCRCs) and metastatic lesions, an...

M Neerincx, D L S Sie, M A van de Wiel, N C T van Grieken, J D Burggraaf… in Oncogenesis (2015)

Article

Response to chemotherapy in patients with recurrent rectal cancer in previously irradiated area

Tumor lesions in previously irradiated area may have a less favorable response to chemotherapy compared to tumor sites outside the radiation field. The aim of the present study was to evaluate the response to ...

W. J. Alberda, B. C. Haberkorn… in International Journal of Colorectal Disease (2015)

Article

Prognostic value of circulating tumour cells for early recurrence after resection of colorectal liver metastases

Despite good outcomes for many, a substantial group of patients undergoing metastasectomy for isolated liver metastases from colorectal cancer (CRC) experience early recurrence. We have investigated whether ci...

Z S Lalmahomed, B Mostert, W Onstenk, J Kraan, N Ayez… in British Journal of Cancer (2015)

Article

Endothelial CD276 (B7-H3) expression is increased in human malignancies and distinguishes between normal and tumour-derived circulating endothelial cells

Mature circulating endothelial cells (CEC) are surrogate markers of endothelial damage. CEC measured in patients with advanced cancer are thought not only to derive from damaged normal vasculature (n-CEC), but...

J Kraan, P van den Broek, C Verhoef, D J Grunhagen, W Taal… in British Journal of Cancer (2014)

Article

Local excision of rectal cancer afterchemoradiation: feasibility depends on the primary stage

J. W. A. Burger, E. J. R. de Graaf… in International Journal of Colorectal Disease (2010)