Skip to main content

2 Result(s)

within Cancer Research Remove this filter Human Genetics Remove this filter Brian M Wolpin Remove this filter Article Remove this filter

and
Your search also matched 5 preview-only Content is preview-only when you or your institution have not yet subscribed to it.

By making our abstracts and previews universally accessible we help you purchase only the content that is relevant to you. results, e.g.

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer

Include preview-only content

  1. Article

    Open Access

    Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma

    The mutant IDH1 inhibitor ivosidenib improves outcomes for patients with IDH1-mutated cholangiocarcinoma, but resistance inevitably develops. Mechanisms of resistance and strategies to overcome resistance are poo...

    James M. Cleary, Betty Rouaisnel, Antoine Daina… in npj Precision Oncology (2022)

    Download PDF (2169 KB) View Article

  2. Article

    Open Access

    A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

    Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% ...

    Evangelina López de Maturana, Juan Antonio Rodríguez, Lola Alonso… in Genome Medicine (2021)

    Download PDF (6792 KB) View Article