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327 Result(s)
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Article
Open AccessGenome-wide atlas of rust resistance loci in wheat
Rust diseases, including leaf rust, stripe/yellow rust, and stem rust, significantly impact wheat (Triticum aestivum L.) yields, causing substantial economic losses every year. Breeding and deployment of cultivar...
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Article
Nutritional and Phytochemical Profiling of Vicia faba L. var. Minor Seeds: a Multifaceted Exploration of Natural Antioxidants and Functional Food Potential
This study explores the nutritional and phytochemical profiling of twenty-three genotypes of Vicia faba L. var. minor seeds cultivated in the experimental field of the Arid Lands Institute of Medenine. Our compre...
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Article
Open AccessACE2 mediates tryptophan alleviation on diarrhea by repairing intestine barrier involved mTOR pathway
The membrane-delimited receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), angiotensin-converting enzyme 2 (ACE2), which is expressed in the intestine, collaborates with broad neutral am...
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Article
MicroRNA-361-5p Alleviates Leydig Cell Apoptosis and Promotes Cell Growth by Targeting PIAS1 in Late-Onset Hypogonadism
Late-onset hypogonadism (LOH) is an age-related syndrome characterized by deficiency of serum testosterone produced by Leydig cells. Previous evidence suggested that microRNA (miR)-361-3p can serve as a promis...
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Impacts of Some Trace Metals in Cyprinus carpio (Linnaeus, 1758) and Tor soro (Valenciennes, 1842) on Human Health
Although fish are rich sources of various trace metals in their bodies, when these metals exceed health safety limits, it becomes a global concern. Fish exposed to trace metal pollution in their aquatic ecosys...
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Article
Monitoring and Health Risk Assessment of Lead and Cadmium in Date Palm Fruit Cultivars Growing in Morocco
The present study aimed to investigate the levels of two toxic trace elements (lead (Pb) and cadmium (Cd)) in 84 date fruit samples of four varieties (Mejhoul, Bouittob, Aziza and Boufegouss) produced in four Mor...
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Article
In-Depth Study of Chemically Electrodeposited Cuprous Oxide (Cu2O) thin Films on ITO Glass
In this contribution, we report the screening of different parameters contributing to the electrodeposition of Cu2O nanostructures as an electrode material to provide an overall understanding of the effect of the...
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Article
Open AccessEnhancing Pisum sativum growth and symbiosis under heat stress: the synergistic impact of co-inoculated bacterial consortia and ACC deaminase-lacking Rhizobium
The 1-aminocyclopropane-1-carboxylate (ACC) deaminase is a crucial bacterial trait, yet it is not widely distributed among rhizobia. Hence, employing a co-inoculation approach that combines selected plant grow...
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Article
A Highly Sensitive Structure Based on Prism, Silver, and Titanium Dioxide for Biochemical Sensing Applications
In this paper, a refractive index (RI) sensor with prism configuration is proposed and numerically investigated for sensing applications. The sensor design is based on a BK7 prism, silver (Ag), and titanium di...
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Article
Improved Expression of a Thermostable GH18 Bacterial Chitinase in Two Different Escherichia coli Strains and Its Potential Use in Plant Protection and Biocontrol of Phytopathogenic Fungi
Chitinases are enzymes that can break down chitin, a major component of the exoskeleton of insects and fungi. This feature makes them potential biopesticides in agriculture since they are considered a safe and...
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Article
Open AccessAssessing the potential of genetic resource introduction into elite germplasm: a collaborative multiparental population for flint maize
Implementing a collaborative pre-breeding multi-parental population efficiently identifies promising donor x elite pairs to enrich the flint maize elite germplasm.
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Article
Relationship Between CD8+ T Cells and Prognosis of Esophageal Cancer Patients: A Systematic Review and Meta-analysis
Tumor infiltrating lymphocytes (TILs), especially CD8+ T cells, play an important role in the process of anti-tumor immune response and are significantly correlated with the prognosis of esophageal cancer (EC)...
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Article
Methods for the Preparation of Silica and Its Nanoparticles from Different Natural Sources
Silica (SiO2), a component of the earth’s crust, has been in use for many nanotechnological applications. This review presents one of the newest methods for safer, more affordable, and more ecologically friendly ...
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Article
Implication of Mn-cofactored superoxide dismutase in the tolerance of swarmer Pseudomonas aeruginosa to polymixin, ciprofloxacin and meropenem antibiotics
The protective role of superoxide dismutase (Sod) against oxidative stress, resulting from the common antibiotic pathway of action, has been studied in the wild type and mutant strains of swarmer Pseudomonas aeru...
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Article
Biodiversity and biotechnological properties of lactic acid bacteria isolated from traditional Moroccan sourdoughs
The present study aimed at characterizing lactic acid bacteria (LAB) strains isolated from traditional sourdoughs collected in different regions of Morocco. Isolated strains were firstly identified using Gram ...
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Article
Hyaluronan and Proteoglycan Link Protein 1 Activates the BMP4/Smad1/5/8 Signaling Pathway to Promote Osteogenic Differentiation: an Implication in Fracture Healing
Osteoblast regeneration, characterized by osteoblast differentiation, is the basis of fracture healing and accelerates fracture repair. It has been reported that hyaluronan and proteoglycan link protein 1 (HAP...
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Article
Isolation and characterization of two glycolipopeptids biosurfactants produced by a Lactiplantibacillus plantarum OL5 strain isolated from green olive curing water
Microbial surfactants are natural amphiphilic compounds with high surface activities and emulsifying properties. Due to their structural diversity, low toxicity, biodegradability, and chemical stability in dif...
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Article
Open AccessLINC00460 Promotes Cutaneous Squamous Cell Carcinoma Progression Through Stabilizing ELAVL1 Protein
Long intergenic noncoding ribonucleic acid (lncRNA) 460 is reportedly associated with carcinogenesis and progression in various types of cancer. However, the mechanisms underlying its action in cutaneous squam...
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Article
Effect of honey bee forage plants in Tunisia on diversity and antibacterial potential of lactic acid bacteria and bifidobacteria from Apis mellifera intermissa and its products
Lactic acid bacteria and bifidobacteria (LAB and Bifido), isolated from the gastrointestinal tract of Apis mellifera intermissa (BGIT), honey (H), propolis (P) and bee bread (BB) of hives set in different vegetat...
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Development of a Cell-based Neutralizing Antibody Assay for Zinpentraxin Alfa: Challenges and Mitigation Strategies
Therapeutic protein drugs can potentially induce immune responses in patients and result in the production of anti-drug antibodies (ADAs), including a subset of ADAs called neutralizing antibodies (NAbs) that ...