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    Article

    The Arf6 activator Efa6/PSD3 confers regional specificity and modulates ethanol consumption in Drosophila and humans

    Ubiquitously expressed genes have been implicated in a variety of specific behaviors, including responses to ethanol. However, the mechanisms that confer this behavioral specificity have remained elusive. Prev...

    D A Gonzalez, T Jia, J H Pinzón, S F Acevedo, S A Ojelade, B Xu in Molecular Psychiatry (2018)

  2. Article

    Open Access

    Disentangling the autism−anxiety overlap: fMRI of reward processing in a community-based longitudinal study

    Up to 40% of youth with autism spectrum disorder (ASD) also suffer from anxiety, and this comorbidity is linked with significant functional impairment. However, the mechanisms of this overlap are poorly unders...

    N Mikita, E Simonoff, D S Pine, R Goodman, E Artiges in Translational Psychiatry (2016)

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    Article

    Genomic architecture of human neuroanatomical diversity

    Human brain anatomy is strikingly diverse and highly inheritable: genetic factors may explain up to 80% of its variability. Prior studies have tried to detect genetic variants with a large effect on neuroanato...

    R Toro, J-B Poline, G Huguet, E Loth, V Frouin, T Banaschewski in Molecular Psychiatry (2015)

  4. Article

    Open Access

    White-matter microstructure and gray-matter volumes in adolescents with subthreshold bipolar symptoms

    Abnormalities in white-matter (WM) microstructure, as lower fractional anisotropy (FA), have been reported in adolescent-onset bipolar disorder and in youth at familial risk for bipolarity. We sought to determ...

    M-L Paillère Martinot, H Lemaitre, E Artiges, R Miranda, R Goodman in Molecular Psychiatry (2014)

  5. Article

    Genetic Risk For Nicotine Dependence in the Cholinergic System and Activation of the Brain Reward System in Healthy Adolescents

    Genetic variation in a genomic region on chromosome 15q25.1, which encodes the alpha5, alpha3, and beta4 subunits of the cholinergic nicotinic receptor genes, confers risk to smoking and nicotine dependence (N...

    F Nees, S H Witt, A Lourdusamy, S Vollstädt-Klein, S Steiner in Neuropsychopharmacology (2013)

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    Article

    Cortical thickness of superior frontal cortex predicts impulsiveness and perceptual reasoning in adolescence

    Impulsiveness is a pivotal personality trait representing a core domain in all major personality inventories. Recently, impulsiveness has been identified as an important modulator of cognitive processing, part...

    C Schilling, S Kühn, T Paus, A Romanowski, T Banaschewski, A Barbot in Molecular Psychiatry (2013)

  7. Article

    Open Access

    The neural basis of video gaming

    Video game playing is a frequent recreational activity. Previous studies have reported an involvement of dopamine-related ventral striatum. However, structural brain correlates of video game playing have not b...

    S Kühn, A Romanowski, C Schilling, R Lorenz, C Mörsen in Translational Psychiatry (2011)