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    Article

    Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity

    Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease characterized by the development of arteriovenous malformations (AVMs) that can result in significant morbidity and mortality. HHT i...

    Anthony R. Anzell, Amy B. Kunz, James P. Donovan, Thanhlong G. Tran in Angiogenesis (2024)

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    Open Access

    Mitochondrial fission and mitophagy are independent mechanisms regulating ischemia/reperfusion injury in primary neurons

    Mitochondrial dynamics and mitophagy are constitutive and complex systems that ensure a healthy mitochondrial network through the segregation and subsequent degradation of damaged mitochondria. Disruption of t...

    Anthony R. Anzell, Garrett M. Fogo, Zoya Gurm, Sarita Raghunayakula in Cell Death & Disease (2021)

  3. Article

    Open Access

    Mitochondrial Quality Control and Disease: Insights into Ischemia-Reperfusion Injury

    Mitochondria are key regulators of cell fate during disease. They control cell survival via the production of ATP that fuels cellular processes and, conversely, cell death via the induction of apoptosis throug...

    Anthony R. Anzell, Rita Maizy, Karin Przyklenk in Molecular Neurobiology (2018)