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  1. No Access

    Article

    Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

    Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has t...

    Caroline M. Nievergelt, Adam X. Maihofer, Elizabeth G. Atkinson… in Nature Genetics (2024)

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    Article

    Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

    Tobacco and alcohol use are leading causes of mortality that influence risk for many complex diseases and disorders1. They are heritable2,3 and etiologically related4,5 behaviors that have been resistant to gene ...

    Mengzhen Liu, Yu Jiang, Robbee Wedow, Yue Li, David M. Brazel, Fang Chen… in Nature Genetics (2019)

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    Article

    Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

    Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic architecture or its genetic relationship with other disorders. To discover loci associated with AD and charact...

    Raymond K. Walters, Renato Polimanti, Emma C. Johnson… in Nature Neuroscience (2018)

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    Article

    Opportunities for an enhanced integration of neuroscience and genomics

    Neuroimaging and genetics are two rapidly expanding fields of research. Thoughtful integration of these areas is critical for ongoing large-scale research into the genetic mechanisms underlying brain structure...

    Ashlee A. Moore, Chelsea Sawyers, Daniel E. Adkins… in Brain Imaging and Behavior (2018)