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Article

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

TP53 mutants (mutp53) are involved in the pathogenesis of most human cancers. Specific mutp53 proteins gain oncogenic functions (GOFs) distinct from the tumor suppressor activity of the wild-type protein. Tumo...

Tomer Cooks, Ioannis S. Pateras, Lisa M. Jenkins, Keval M. Patel… in Nature Communications (2018)