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Open AccessIntegrative genetic and genomic networks identify microRNA associated with COPD and ILD
Chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) are clinically and molecularly heterogeneous diseases. We utilized clustering and integrative network analyses to elucidate role...
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Open AccessGenetic load makes cancer cells more sensitive to common drugs: evidence from Cancer Cell Line Encyclopedia
Genetic alterations initiate tumors and enable the evolution of drug resistance. The pro-cancer view of mutations is however incomplete, and several studies show that mutational load can reduce tumor fitness. ...