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Article
Open AccessCulture independent molecular analysis of bacterial communities in the mangrove sediment of Sundarban, India
Sundarban is the world's largest coastal sediment comprising of mangrove forest which covers about one million hectares in the south-eastern parts of India and southern parts of Bangladesh. The microbial diver...
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Article
Open AccessNext generation sequencing based identification of disease-associated mutations in Swiss patients with retinal dystrophies
Inherited monogenic diseases of the retina and vitreous affect approximately 1 in 2000 individuals. They are characterized by tremendous genetic heterogeneity and clinical variability involving mutations in ap...
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Article
Synthesis and evaluation of selected 1,3,4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity
The oxadiazole moiety is known for its anticancer activity through its antiangiogenic and mitostatic potential. Taking this as a cue, the present study was designed to investigate the anti-cancer potential of ...
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Article
Preparation, Characterization, and In vitro Evaluation of Curcumin- and Resveratrol-Loaded Solid Lipid Nanoparticles
Curcumin and resveratrol are natural compounds with significant anticancer activity; however, their bioavailability is limited due to poor solubility. This study aimed to overcome the solubility problem by mea...
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Article
Open AccessMuon \(\mathbf {g-2}\) , neutralino dark matter and stau NLSP
We explore the implications of resolving the muon \(g-2\) g - ...
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Open AccessComposite topological structures in SO(10)
We explore a variety of composite topological structures that arise from the spontaneous breaking of SO(10) to SU(3)c × U(1)em via one of its maximal subgroups SU(5) × U(1)χ, SU(4)c × SU(2)L × SU(2)R, and SU(5) ×
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Article
Smart Investigations into the Development of an Effective Computer-Assisted Diagnosis System for CT Scan Brain Depictions
Recent advances in medical image analysis on computers are anticipated to help radiologists and other healthcare workers with numerous diagnostic tasks including medical image interpretation. Accurate diagnosi...
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Open AccessValidation of hypermethylated DNA regions found in colorectal cancers as potential aging-independent biomarkers of precancerous colorectal lesions
We previously identified 16,772 colorectal cancer-associated hypermethylated DNA regions that were also detectable in precancerous colorectal lesions (preCRCs) and unrelated to normal mucosal aging. We have no...
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Article
Quality Management of Probiotics: Ensuring Safety and Maximizing Health Benefits
Consumption of probiotics, which are beneficial live microorganisms, has received a lot of attention because of their potential to improve health and wellness. Robust quality control measures are necessary to ...