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Article

Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1

Many mutant p53 proteins exert oncogenic gain-of-function (GOF) properties that promote cancer cell invasive growth and metastasis, yet the mechanisms mediating these functions still largely remain elusive. We...

Noriaki Tanaka, Mei Zhao, Lin Tang, Ameeta A. Patel, Qing **, Hieu T. Van… in Oncogene (2018)