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    Open Access

    Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis

    We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors’ aggre...

    Mina Waraya, Keishi Yamashita, Hiroshi Katoh, Akira Ooki, Hiroshi Kawamata… in BMC Cancer (2012)

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