1 Result(s)

Article

Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients

As a component of the apoptosome, a caspase-activating complex, Apaf-1 plays a central role in the mitochondrial caspase activation pathway of apoptosis. We report here the identification of a novel Apaf-1 int...

V Piddubnyak, P Rigou, L Michel, J-C Rain, O Geneste… in Cell Death & Differentiation (2007)