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Article
Expression of Collagen IV, Fibronectin, Laminin in Non-small Cell Lung Cancer and Its Correlation with Chemosensitivities and Apoptosis
Objective: To study the expression of extracellular matrix (ECM) proteins including Collagen IV (Co IV), Fibronectin, Laminin in human non-small cell lung cancer (NSCLC) specimens and the relationship between ...
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Article
Expressions and clinicopathologic significance of five heat shock proteins in esophageal squamous cell carcinoma
To investigate the expressions of heat shock protein (hsp) 10, hsp27, hsp60, hsp70 and hsp90α in esophageal squamous cell carcinoma (ESCC) and normal tissues along the incisal margin (TIM), and discuss the cli...
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Article
Clinical significance of heat shock protein 10 in large bowel carcinoma
To investigate the expression of heat shock protein 10 (HSP10) during genesis and development of large bowel carcinoma and discuss the clinical significance about its expression.
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Article
Prognostic Significance of Microscopic Positive Margins for Gastric Cancer Patients with Potentially Curative Resection
Most previous studies concerning the impact of positive margins on patient outcomes were based on patients with D1 lymphadenectomy. The prognostic significance of positive margins for patients with D2/D3 lymph...
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Article
Advanced Gastric Cancer with Early Cancer Macroscopic Appearance: Is It Worthy of D2 Lymphadenectomy?
Previous studies report that 5.9–22.2% of patients with preoperatively diagnosed early gastric cancers were eventually proven to have advanced gastric cancers by postoperative pathological examination. Such mi...
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Article
Macroscopic Serosal Classification Predicts Peritoneal Recurrence for Patients with Gastric Cancer Underwent Potentially Curative Surgery
Previous studies revealed serosal invasion as one of the most important predictors of peritoneal micrometastasis. However, even for cancers with serosal invasion, the macroscopic serosal appearance is highly h...
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Article
Food intake and interdigestive gastrointestinal motility in ghrelin receptor mutant rats
Ghrelin is the endogenous ligand for the growth hormone secretagogue receptor (GHSR). Ghrelin regulates feeding activity and interdigestive contractions of the stomach in rodents. To investigate the role of en...
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Article
Evaluation of the Seventh Edition of American Joint Committee on Cancer TNM Staging System for Gastric Cancer: Results from a Chinese Monoinstitutional Study
To investigate the validity of the 7th edition of American Joint Committee on Cancer (AJCC) TNM staging system for gastric cancer with special attention paid to pT2/pT3, pN1/pN2, and pN3a/pN3b category.
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Article
IL-23R polymorphisms, HBV infection, and risk of hepatocellular carcinoma in a high-risk Chinese population
The interleukin-23 receptor (IL-23R) plays an important role in the T-helper 17 cell-mediated inflammatory process and is also involved in tumor immune surveillance, which may be linked to carcinogenesis in he...
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Article
Open AccessMammotome-assisted endoscopic breast-conserving surgery: a novel technique for early-stage breast cancer
Because of its minimally invasive and highly accurate nature, the use of Mammotome, a vacuum-assisted breast biopsy device has proven beneficial to the treatment of benign breast lesions. Taking advantage of e...
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Article
Combined application of diclofenac and celecoxib with an opioid yields superior efficacy in metastatic bone cancer pain: a randomized controlled trial
Metastatic bone cancer pain is one of the most common clinical cancer pains and is caused by many factors. This study was conducted to explore the clinical efficacy of using two non-steroidal anti-inflammator...
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Article
Tumor-associated macrophage infiltration is highly associated with PD-L1 expression in gastric adenocarcinoma
Programmed death ligand 1 (PD-L1) is a key protein upregulated by tumor cells to suppress immune responses. Tumor-associated macrophages (TAMs) play a major role in this immunosuppression, but the relationship...
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Article
Open AccessCombined detection of serum autoantibodies as diagnostic biomarkers in esophagogastric junction adenocarcinoma
We previously found that autoantibodies against a panel of six tumor-associated antigens (p53, NY-ESO-1, MMP-7, Hsp70, PRDX6 and Bmi-1) may aid in early detection of esophageal squamous cell carcinoma. Here we...
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Article
Open AccessLaparoscopic pancreaticoduodenectomy: are the best times coming?
The introduction of laparoscopic technology has greatly promoted the development of surgery, and the trend of minimally invasive surgery is becoming more and more obvious. However, there is no consensus as to ...
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Article
Lymph Node Station-Based Nodal Staging System for Esophageal Squamous Cell Carcinoma: A Large-Scale Multicenter Study
The American Joint Committee on Cancer (AJCC) nodal staging for esophageal squamous cell carcinoma (ESCC) has been defined by the number of metastatic lymph nodes (N system). However, the precise counting of i...
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Article
Open AccessA computer-aided diagnosing system in the evaluation of thyroid nodules—experience in a specialized thyroid center
The evaluation of thyroid nodules with ultrasonography has created a large burden for radiologists. Artificial intelligence technology has been rapidly developed in recent years to reduce the cost of labor and...
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Article
Laparoscopic versus abdominal radical hysterectomy for stage IB1 cervical cancer patients with tumor size ≤ 2 cm: a case-matched control study
To investigate the survival outcomes of stage IB1 cervical cancer patients with tumor size ≤ 2 cm who underwent laparoscopic or abdominal radical hysterectomy.
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Article
SAMD14 promoter methylation is strongly associated with gene expression and poor prognosis in gastric cancer
Gastric cancer (GC) is the fifth most common malignancy worldwide and the third leading cause of cancer-related mortality. In recent years, SAMD14 has been studied in various malignant cancers; however, little is...
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Article
Expression of SARS-CoV-2 receptor ACE2 and TMPRSS2 in human primary conjunctival and pterygium cell lines and in mouse cornea
To determine the expressions of SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) and type II transmembrane serine protease (TMPRSS2) genes in human and mouse ocular cells and comparison to other tissue ...
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Article
LINC00943 is correlated with gastric cancer and regulates cancer cell proliferation and chemosensitivity via hsa-miR-101-3p
Non-coding RNAs have emerged as important regulators in human cancers. In this work, we investigated the role of long intergenic non-protein-coding RNA 943 (LINC00943) in gastric cancer (GC).