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Article
Open AccessCombined detection of serum autoantibodies as diagnostic biomarkers in esophagogastric junction adenocarcinoma
We previously found that autoantibodies against a panel of six tumor-associated antigens (p53, NY-ESO-1, MMP-7, Hsp70, PRDX6 and Bmi-1) may aid in early detection of esophageal squamous cell carcinoma. Here we...
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Article
Tumor-associated macrophage infiltration is highly associated with PD-L1 expression in gastric adenocarcinoma
Programmed death ligand 1 (PD-L1) is a key protein upregulated by tumor cells to suppress immune responses. Tumor-associated macrophages (TAMs) play a major role in this immunosuppression, but the relationship...
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Article
IL-23R polymorphisms, HBV infection, and risk of hepatocellular carcinoma in a high-risk Chinese population
The interleukin-23 receptor (IL-23R) plays an important role in the T-helper 17 cell-mediated inflammatory process and is also involved in tumor immune surveillance, which may be linked to carcinogenesis in he...
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Article
Food intake and interdigestive gastrointestinal motility in ghrelin receptor mutant rats
Ghrelin is the endogenous ligand for the growth hormone secretagogue receptor (GHSR). Ghrelin regulates feeding activity and interdigestive contractions of the stomach in rodents. To investigate the role of en...