37 Result(s)
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Life Sciences
Biotechnology
Microbiology
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Article
Open AccessAdaptive responses of erythritol-producing Yarrowia lipolytica to thermal stress after evolution
Elucidation of the thermotolerance mechanism of erythritol-producing Yarrowia lipolytica is of great significance to breed robust industrial strains and reduce cost. This study aimed to breed thermotolerant Y. li...
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Systematic analysis on the mechanism of Zhizi-Bopi decoction against hepatitis B via network pharmacology and molecular docking
Purpose: Zhizi-Bopi decoction (ZZBPD) is a classic herbal formula with wide clinical applications in treating liver diseases including hepatitis B. However, the mechanism needs to be elucidated.
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Cephalosporin C biosynthesis and fermentation in Acremonium chrysogenum
Cephalosporins are currently the most widely used antibiotics in clinical practice. The main strain used for the industrial production cephalosporin C (CPC) is Acremonium chrysogenum. CPC has the advantages of po...
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Enhancing regioselectivity of sucrose phosphorylase by loop engineering for glycosylation of l-ascorbic acid
Sucrose phosphorylase (SPase) has a remarkable capacity to synthesize numerous glucosides from abundantly available sucrose under mild conditions but suffers from specificity and regioselectivity issues. In th...
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Structure and stability analysis of antibacterial substance produced by selenium enriched Bacillus cereus BC1
Microorganisms can produce many antibiotics against bacteria and fungi, which have been used as a potential choice of new antibiotics. In this paper, we studied the characteristics of antibacterial substances by
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Characterization and genomic analysis of a Demerecviridae phage SP76 with lytic multiple-serotypes of Salmonella
With the increase in antimicrobial resistance of Salmonella, phages have been paid more attention to as an alternative to antibiotics. In this study, a phage designated as SP76 was isolated from sewage. It can ly...
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The effectiveness of extended binding affinity of prophage lysin PlyARI against Streptococcus suis infection
Streptococcus suis is an important zoonotic pathogen. An increase in multi-drug-resistant strains has led to poor performance of traditional antibiotic therapies. Thus, alternative antibacterial agents are urgent...
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Efficient production of l-menthyl α-glucopyranoside from l-menthol via whole-cell biotransformation using recombinant Escherichia coli
l-Menthyl α-D-glucopyranoside (α-MenG) is a glycoside derivative of l-menthol with improved water-solubility and new flavor property as a food additive. α-MenG can be synthesized through biotransformation, but it...
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Role of rgsA in Oxidative Stress Resistance in Pseudomonas aeruginosa
Pseudomonas aeruginosa is a common opportunistic pathogen that causes infections in vulnerable patients including those with metabolic disorders, hematologic diseases, and malignancies, and in those who have unde...
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MrPEX33 is involved in infection-related morphogenesis and pathogenicity of Metarhizium robertsii
Peroxisomes, being indispensable organelles, play an important role in different biological processes in eukaryotes. PEX33, a filamentous fungus-specific peroxin of the docking machinery of peroxisomes, is inv...
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Open AccessTabersonine ameliorates osteoblast apoptosis in rats with dexamethasone-induced osteoporosis by regulating the Nrf2/ROS/Bax signalling pathway
We explored how tabersonine (Tab) protected against dexamethasone (Dex)-induced osteoporosis. Osteoblasts were treated with Dex (100 µM) with or without Table (5 or 10 µM). We measured cell viability, alkaline...
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Colorimetric detection of Hg2+ using gold nanoparticles synthesized by Trichosporon montevideense WIN
To investigate a simple, cost-effective and eco-friendly method for colorimetric detection of Hg2+ using gold nanoparticles (AuNPs) synthesized by Trichosporon montevideense WIN.
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An Insight into Diversity and Functionalities of Gut Microbiota in Insects
The gut microbiota has long been of research interests due to its nutritional importance for many insects. It has been demonstrated that diversity of gut microbiota in insects can be modulated by many factors,...
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Open AccessInfluence of metals and metalloids on the composition and fluorescence quenching of the extracellular polymeric substances produced by the polymorphic fungus Aureobasidium pullulans
Aureobasidium pullulans is a ubiquitous and widely distributed fungus in the environment, and exhibits substantial tolerance against toxic metals. However, the interactions between metals and metalloids with the ...
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Open AccessMicroplastics provide new microbial niches in aquatic environments
Microplastics in the biosphere are currently of great environmental concern because of their potential toxicity for aquatic biota and human health and association with pathogenic microbiota. Microplastics can ...
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Regulation and controlling the motility properties of Pseudomonas aeruginosa
Chronic infections caused by Pseudomonas aeruginosa have been a major concern as their spread and mortality continue to be on the rise. These infections are majorly attributed to biofilm formation via sequential ...
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Open AccessBiorecovery of cobalt and nickel using biomass-free culture supernatants from Aspergillus niger
In this research, the capabilities of culture supernatants generated by the oxalate-producing fungus Aspergillus niger for the bioprecipitation and biorecovery of cobalt and nickel were investigated, as was the i...
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Open AccessOptimization of whole-cell biotransformation for scale-up production of α-arbutin from hydroquinone by the use of recombinant Escherichia coli
α-Arbutin is an effective skin-whitening cosmetic ingredient and hyperpigmentation therapy agent. It can be synthesized by one-step enzymatic glycosylation of hydroquinone (HQ), but limited by the low yield. A...
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Purification-independent immunoreagents obtained by displaying nanobodies on bacteria surface
The availability of preimmune libraries of antibody fragments allows for the fast generation of binders which can be expressed in both eukaryotic and prokaryotic systems. We exploited the recombinant nature of...
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The attachment potential and N-acyl-homoserine lactone-based quorum sensing in aerobic granular sludge and algal-bacterial granular sludge
Bacteria and algae often coexist in the aerobic granular sludge (AGS) system in a photo-bioreactor, forming algal-bacterial granular sludge. In this study, the physicochemical characteristics and microbial att...
