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Article
Open AccessPermissive effect of GSK3β on profibrogenic plasticity of renal tubular cells in progressive chronic kidney disease
Renal tubular epithelial cells (TECs) play a key role in renal fibrogenesis. After persistent injuries that are beyond self-healing capacity, TECs will dedifferentiate, undergo growth arrest, convert to profib...
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Article
Melanocortin 5 receptor signaling pathway in health and disease
Melanocortin hormone system plays a key role in maintaining the homeostasis of our body via their neuro-immune-endocrine activities and regulates a diverse array of physiological functions, including melanogen...
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Article
Open AccessRNA-binding proteins tristetraprolin and human antigen R are novel modulators of podocyte injury in diabetic kidney disease
Diabetic kidney disease (DKD) is one of the most common complications of diabetes, and the most common cause of end-stage renal disease, for which no effective therapies are yet available. RNA-binding proteins...
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Article
Middle Pleistocene mammalian fauna of Shanyangzhai cave in Qinhuangdao area, China and its zoogeographical significance
The mammalian fauna with clear characteristics of transitional region has been found in the Shanyangzhai cave of the Qinhuangdao area where the three Chinese zoogeographical regions (the Northeast region, the ...