15 Result(s)
within
Article
**nlong Zhou
English
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessCarbon Monitor Europe near-real-time daily CO2 emissions for 27 EU countries and the United Kingdom
With the urgent need to implement the EU countries pledges and to monitor the effectiveness of Green Deal plan, Monitoring Reporting and Verification tools are needed to track how emissions are changing for al...
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Open AccessOncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity
The advantage of oncolytic viruses (OV) in cancer therapy is their dual effect of directly killing tumours while prompting anti-tumour immune response. Oncolytic parapoxvirus ovis (ORFV) and other OVs are thou...
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Open AccessIn situ analysis of nanoparticle soft corona and dynamic evolution
How soft corona, the protein corona’s outer layer, contributes to biological identity of nanomaterials is largely because capturing protein composition of the soft corona in situ remains challenging. We herein...
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Open AccessIdentification of PIEZO1 as a potential prognostic marker in gliomas
In multiple solid tumours, including gliomas, the mechanical properties change as the disease progresses. If and how mechanical cues regulate tumour cell proliferation is currently not fully studied. PIEZO1 ha...
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Open AccessCombination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma
Neurofibromatosis type 2 (NF2) is an inherited disorder characterized by bilateral vestibular schwannomas (VS) that arise from neoplastic Schwann cells (SCs). NF2-associated VSs are often accompanied by mening...
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Open AccessMTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing
The metabolic switch from oxidative phosphorylation to glycolysis is required for tumorigenesis in order to provide cancer cells with energy and substrates of biosynthesis. Therefore, it is important to elucid...
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Open AccessComputational delineation and quantitative heterogeneity analysis of lung tumor on 18F-FDG PET for radiation dose-escalation
Quantitative measurement and analysis of tumor metabolic activities could provide a more optimal solution to personalized accurate dose painting. We collected PET images of 58 lung cancer patients, in which th...
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Open AccessAcrolein-stressed threshold adaptation alters the molecular and metabolic bases of an engineered Saccharomyces cerevisiae to improve glutathione production
Acrolein (Acr) was used as a selection agent to improve the glutathione (GSH) overproduction of the prototrophic strain W303-1b/FGPPT. After two rounds of adaptive laboratory evolution (ALE), an unexpected result...
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Open AccessUnusual multiscale mechanics of biomimetic nanoparticle hydrogels
Viscoelastic properties are central for gels and other materials. Simultaneously, high storage and loss moduli are difficult to attain due to their contrarian requirements to chemical structure. Biomimetic ino...
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Open AccessLong noncoding RNA CASC9.5 promotes the proliferation and metastasis of lung adenocarcinoma
Long non-coding RNAs (lncRNAs) are important regulatory factors in tumor development and progression. The lncRNA CASC9.5 is located on chromosome 8 and has a total length of 1316 bp. CASC9.5 plays a tumor-prom...
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Open AccessAuPt Alloy Nanostructures with Tunable Composition and Enzyme-like Activities for Colorimetric Detection of Bisulfide
Tuning the enzyme-like activity and studying the interaction between biologically relevant species and nano-enzymes may facilitate the applications of nanostructures in mimicking natural enzymes. In this work,...
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Open AccessThe preparation and characterization of a novel sphingan WL from marine Sphingomonas sp. WG
Sphingans, a group of structurally closely related bacterial exopolysaccharides produced by members of the genus Sphingomonas, can be applied in a variety of industries such as food, cement, and personal care app...
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Open AccessStructural Evolution of Nanoscale Zero-Valent Iron (nZVI) in Anoxic Co2+ Solution: Interactional Performance and Mechanism
The structures of nanoscale zero-valent iron (nZVI) particles evolving during reactions and the reactions are influenced by the evolved structures. To understand the removal process in detail, it is important ...
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Open AccessVirtual finger boosts three-dimensional imaging and microsurgery as well as terabyte volume image visualization and analysis
Three-dimensional (3D) bioimaging, visualization and data analysis are in strong need of powerful 3D exploration techniques. We develop virtual finger (VF) to generate 3D curves, points and regions-of-interest...
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Genetic and structural analyses suggest that a novel SPG3A mutation causes severe phenotypes of hereditary spastic paraplegia
Hereditary spastic paraplegia (HSP) is a group of neurodegenerative diseases. The genotypes and phenotypes of HSP are extremely heterogenous. SPG3A is one of the identified genes underlying HSP, and codes for a G...
