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Article
Open AccessConditional knockdown of OsMLH1 to improve plant prime editing systems without disturbing fertility in rice
High-efficiency prime editing (PE) is desirable for precise genome manipulation. The activity of mammalian PE systems can be largely improved by inhibiting DNA mismatch repair by coexpressing a dominant-negati...
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Article
A genomic variation map provides insights into the genetic basis of cucumber domestication and diversity
Sanwen Huang and colleagues report a genomic variation map of cucumber. They report the resequencing of 115 cucumber accessions and de novo assembly of the wild cucumber genome.
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Article
The genome of the cucumber, Cucumis sativus L.
Jun Wang and colleagues report the genome sequence of the cucumber. The cucumber genome is the seventh plant genome sequence to be reported and was assembled with a combination of traditional Sanger and next-g...