628 Result(s)
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**ng-shen Chen
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Open AccessLow-input PacBio sequencing generates high-quality individual fly genomes and characterizes mutational processes
Long-read sequencing, exemplified by PacBio, revolutionizes genomics, overcoming challenges like repetitive sequences. However, the high DNA requirement ( > 1 µg) is prohibitive for small organisms. We develop...
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Open AccessBrain effect mechanism of lever positioning manipulation on LDH analgesia based on multimodal MRI: a study protocol
The clinical symptoms of Lumbar Disc Herniation (LDH) can be effectively ameliorated through Lever Positioning Manipulation (LPM), which is closely linked to the brain's pain-regulating mechanisms. Magnetic Re...
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Open AccessCommon dietary emulsifiers promote metabolic disorders and intestinal microbiota dysbiosis in mice
Dietary emulsifiers are linked to various diseases. The recent discovery of the role of gut microbiota–host interactions on health and disease warrants the safety reassessment of dietary emulsifiers through th...
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Open AccessSurgical outcomes of robotic-assisted percutaneous fixation for thoracolumbar fractures in patients with ankylosing spondylitis
Spinal fractures in patients with ankylosing spondylitis (AS) mainly present as instability, involving all three columns of the spine, and surgical intervention is often considered necessary. However, in AS pa...
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Open AccessPrognostic value of the Naples prognostic score in patients with intrahepatic cholangiocarcinoma after hepatectomy
The Naples Prognostic Score (NPS), integrating inflammatory and nutritional biomarkers, has been reported to be associated with the prognosis of various malignancies, but there is no report on intrahepatic cho...
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PARP-2 mediates cardiomyocyte aging and damage induced by doxorubicin through SIRT1 Inhibition
Doxorubicin (DOX) is an anthracycline antibiotic used as an antitumor treatment. However, its clinical application is limited due to severe side effects such as cardiotoxicity. In recent years, numerous studie...
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Cross-ancestry genome-wide association studies of brain imaging phenotypes
Genome-wide association studies of brain imaging phenotypes are mainly performed in European populations, but other populations are severely under-represented. Here, we conducted Chinese-alone and cross-ancest...
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Open AccessCritical roles of tubular mitochondrial ATP synthase dysfunction in maleic acid-induced acute kidney injury
Maleic acid (MA) induces renal tubular cell dysfunction directed to acute kidney injury (AKI). AKI is an increasing global health burden due to its association with mortality and morbidity. However, targeted t...
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Advances in understanding quantum dot light-emitting diodes
Quantum dot light-emitting diodes (QD-LEDs) are attractive for display and lighting applications owing to their high colour rendering index, their low-cost solution processability and their ability to achieve ...
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Structural and functional properties of Maillard-reacted casein phosphopeptides with different carbohydrates
This study used glucose, fructose, maltose and dextran to explore the effects of different carbohydrates on the Maillard reaction of casein phosphopeptides (CPP). The color parameter results showed that heatin...
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Open AccessStructural basis of a small monomeric Clivia fluorogenic RNA with a large Stokes shift
RNA-based fluorogenic modules have revolutionized the spatiotemporal localization of RNA molecules. Recently, a fluorophore named 5-((Z)-4-((2-hydroxyethyl)(methyl)amino)benzylidene)-3-methyl-2-((E)-styryl)-3,5-d...
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Stepped-up development of accelerator mass spectrometry method for the detection of 60Fe with the HI-13 tandem accelerator
The Moon provides a unique environment for investigating nearby astrophysical events such as supernovae. Lunar samples retain valuable information from these events, via detectable long-lived “fingerprint” rad...
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Analytical computation of magnetic field in coil-dominated superconducting quadrupole magnets based on racetrack coils
Currently, three types of superconducting quadrupole magnets are used in particle accelerators: \(\cos {2\theta }\) ...
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Open AccessSearch for new particles in final states with a boosted top quark and missing transverse momentum in proton-proton collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
A search for events with one top quark and missing transverse momentum in the final state is presented. The fully hadronic decay of the top quark is explored by selecting events with a reconstructed boosted to...
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Open AccessIdentification of neurological complications in childhood influenza: a random forest model
Among the neurological complications of influenza in children, the most severe is acute necrotizing encephalopathy (ANE), with a high mortality rate and neurological sequelae. ANE is characterized by rapid pro...
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Open AccessElectron and photon efficiencies in LHC Run 2 with the ATLAS experiment
Precision measurements of electron reconstruction, identification, and isolation efficiencies and photon identification efficiencies are presented. They use the full Run 2 data sample collected by the ATLAS ex...
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Open AccessExploring ALK fusion in colorectal cancer: a case series and comprehensive analysis
Anaplastic lymphoma kinase (ALK) fusion-positive colorectal cancer (CRC) is a rare and chemotherapy-refractory subtype that lacks established and effective treatment strategies. Additionally, the efficacy and ...
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Open AccessTunable magnetism in titanium-based kagome metals by rare-earth engineering and high pressure
Rare-earth engineering is an effective way to introduce and tune magnetism in topological kagome materials, which have been acting as a fertile platform to investigate the quantum interactions between geometry...
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Open AccessATLAS Run 2 searches for electroweak production of supersymmetric particles interpreted within the pMSSM
A summary of the constraints from searches performed by the ATLAS collaboration for the electroweak production of charginos and neutralinos is presented. Results from eight separate ATLAS searches are consider...
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High levels of soil calcium and clay facilitate the recovery and stability of organic carbon: Insights from different land uses in the karst of China
Soil organic carbon (SOC) is a crucial medium of the global carbon cycle and is profoundly affected by multiple factors, such as climate and management practices. However, interactions between different SOC fr...
